Armeniacae Semen Regulates Apoptosis and Cell Cycle Progression in MCF-7, MDA-MB-231, and T47D Breast Cancer Cell Lines [PDF]
Background: Amygdalin is a glycoside ingredient of rosacea plants that exerts an antitumor effect by blocking the growth of the tumor cells. Therefore, we aimed to use the Armeniacae semen, a member of the Rosacea family, which contains a large amount of
Shiva Mosadegh Manshadi +2 more
doaj +1 more source
Expression of Bcl-2-family proteins in peripheral blood B-lymphocytes in patients with cronic lymphocytic leukemia [PDF]
Chronic lymphocytic leukemia (CLL) is a neoplastic disease characterized by the accumulation of morphologically mature monoclonal CD 5+ B cells in the early phase (G0/G1) of the cell cycle.
Brajušković Goran R. +7 more
doaj +1 more source
Bcl-2 and Bax interaction in B-lymphocytes of peripheral blood in patients with chronic lymphocytic leukemia [PDF]
Background. Chronic lymphocytic leukemia (CLL) is a neoplastic disease characterized by the accumulation of morphologically mature monoclonal CD5+ B cells in the early phase (G0/G1) of the cell cycle.
Brajušković Goran R. +5 more
doaj +1 more source
LINFOMA DE ZONA MARGINAL (MALT) EM GLÂNDULA LACRIMAL - UM RELATO DE CASO
Objetivos: O propósito deste estudo é divulgar os conhecimentos sobre um caso raro de linfoma de zona marginal (MALT) em glândula lacrimal, visando ampliar o conhecimento sobre essa doença no meio científico.
PC Gontijo +6 more
doaj +1 more source
Selective induction of cell death in melanoma cell lines through targeting of Mcl-1 and A1. [PDF]
Melanoma is an often fatal form of skin cancer which is remarkably resistant against radio- and chemotherapy. Even new strategies that target RAS/RAF signaling and display unprecedented efficacy are characterized by resistance mechanisms.
Berking, Carola +18 more
core +1 more source
BACKGROUND: Higher proliferation is commonly observed in cancer cells. Apoptosis can be a useful measure of a tumor cell kinetic. Alteration of the balance between proliferation and apoptosis is associated with cancer.
Nora Manoukian Forones +4 more
doaj +1 more source
Suppression of signal transducer and activator of transcription 3-dependent B lymphocyte terminal differentiation by BCL-6 [PDF]
Lymphocytes usually differentiate into effector cells within days after antigen exposure, except in germinal centers where terminal differentiation is delayed while somatic hypermutation creates high-affinity antibody mutants. Here we investigate whether
Peakman, LJ +14 more
core +1 more source
Effect and mechanism of Juluo decoction combined with Ruhe powder in treatment of rat model of hyperplasia of mammary glands [PDF]
Objective To investigate the effect and mechanism of Juluo Decoction combined with Ruhe Powder in the treatment of rat model of hyperplasia of mammary glands.
NIE Weihong, LIU Hongxi, SUN Guoxin, LIU Chengcong, ZOU Xiao
doaj +1 more source
Roles of Bcl-3 in the pathogenesis of murine type 1 diabetes [PDF]
OBJECTIVE: It has long been recognized that autoimmunity is often associated with immunodeficiency. The mechanism underlying this paradox is not well understood.
Ruaidhri J. Carmody +9 more
core +1 more source
Ets-2 is a target for an Akt (protein kinase B)/Jun N-terminal kinase signaling pathway in macrophages of motheaten-viable mutant mice [PDF]
The transcription factor ets-2 was phosphorylated at residue threonine 72 in a colony-stimulating factor 1 (CSF-1)- and mitogen-activated protein kinase-independent manner in macrophages isolated from motheaten-viable (me-v) mice.
Forsthoefel, David +16 more
core +1 more source

