Results 11 to 20 of about 83,854 (161)

Sequential induction of NF-κB/Rel family proteins during B-cell terminal differentiation [PDF]

, 1994
The NF-kappa B/Rel family of at least five transcription factor polypeptides is thought to function both as a developmental regulator in B cells and as a rapid response system in all cells. To examine this notion in more detail, we determined the protein
Baltimore, David, Liou, Hsiou-Chi, Scott, Martin L., Sha, William C.   +3 more
core   +1 more source

Overexpression of an activated REL mutant enhances the transformed state of the human B-lymphoma BJAB cell line and alters its gene expression profile [PDF]

, 2009
The human REL proto-oncogene encodes a transcription factor in the nuclear factor (NF)-kappaB family. Overexpression of REL is acutely transforming in chicken lymphoid cells, but has not been shown to transform any mammalian lymphoid cell type.
Chin, M., Gilmore, T.D., Herscovitch, M., Waxman, D.J., Zhang, N.   +4 more
core   +5 more sources

Bcl-2 expression in rectal cancer Expressão da proteína bcl-2 no câncer de reto

Arquivos de Gastroenterologia, 2006
BACKGROUD: Proteins involved in apoptosis process seem to play an important role in colorectal carcinogenesis AIM: To determine the prevalence of bcl-2 protein immunohistochemical expression and its relation with clinical and histopathological variables ...
Paulo C. Contu, Simone S. Contu, Luis F. Moreira   +2 more
doaj   +1 more source

Is now the time for molecular driven therapy for diffuse large B-cell lymphoma? [PDF]

, 2017
INTRODUCTION: Recent genetic and molecular discoveries regarding alterations in diffuse large B-cell lymphoma (DLBCL) deeply changed the approach to this lymphoproliferative disorder.
Ansuinelli, Michela, DE ANGELIS, Federico, DI ROCCO, Alice, Foa, Roberto, Martelli, Maurizio   +4 more
core   +1 more source

Analysis of the immunohistochemical expressions of p53, bcl-2 and Ki-67 in colorectal adenocarcinoma and their correlations with the prognostic factors Análise das expressões imunoistoquímicas da p53, bcl-2 e Ki-67 no adenocarcinoma colorretal e suas correlações com os fatores prognósticos

Arquivos de Gastroenterologia, 2010
CONTEXT: Search of tumors markers that allow treatment with higher survival rates, and indicate the response to treatment and recurrence of cancer OBJECTIVE: To analyze the immunoexpression of the proteins p53, bcl-2 and Ki-67 in colorectal ...
Hunaldo Lima de Menezes, Mário Jorge Jucá, Edmundo Guilherme de A. Gomes, Benício L. Bulhões B. P. Nunes, Henrique Oliveira Costa, Delcio Matos   +5 more
doaj   +1 more source

The Nefarious Nexus of Noncoding RNAs in Cancer [PDF]

, 2018
The past decade has witnessed enormous progress, which has seen the noncoding RNAs (ncRNAs) turn from the so called dark matter RNA to critical functional molecules, influencing most physiological processes in development and disease contexts.
Anastasiadou, Eleni, Faggioni, Alberto, J Slack, Frank, Trivedi, Pankaj   +3 more
core   +1 more source

Evaluation of Some Prognostic Biomarkers in Human Papillomavirus-Related Multiphenotypic Sinonasal Carcinoma [PDF]

Iranian Journal of Medical Sciences
Background: Human papillomavirus (HPV)-related multi phenotypic sinonasal carcinoma (HMSC) is a recently described tumor subtype with an unknown prognosis, often misdiagnosed with other sinonasal carcinomas, and associated with high-risk HPV (HR-HPV ...
Mohamed Ali Alabiad, Warda M. M. Said, Amal M. A. Adim, Mohammed Alorini, Amany Mohamed Shalaby, Walaa Samy, Shereen Elshorbagy, Doaa Mandour, Ibrahim Mohamed Saber, Amar Ibrahim Omar Yahia, Dina Ahmed Khairy   +10 more
doaj   +1 more source

Adenocarcinoma of the esophagogastric junction: relationship between clinicopathological data and p53, cyclin D1 and Bcl-2 immunoexpressions Adenocarcinoma da junção esôfago-gástrica: relação entre os dados cllnipatológicos e a imunoexpressão de p53, ciclina D1 e Bcl-2

Arquivos de Gastroenterologia, 2009
CONTEXT: Esophagogastric junction adenocarcinoma has an aggressive behavior, and TNM (UICC) staging is not always accurate enough to categorize patient's outcome.
Dárcio Matenhauer Lehrbach, Ivan Cecconello, Ulysses Ribeiro Jr, Vera Luiza Capelozzi, Alexandre Muxfeldt Ab'Saber, Venâncio Avancini Ferreira Alves   +5 more
doaj   +1 more source

Bcl-3 deficiency protects against dextran-sodium sulphate-induced colitis in the mouse [PDF]

, 2013
Bcl-3 is a member of the IκB family of proteins and is an essential negative regulator of Toll-like receptor induced responses. Recently, a single nucleotide polymorphism associated with reduced Bcl-3 gene expression has been identified as a potential ...
Araki, Carmody, Costello, Cummins, Dann, Fransen, Ghosh, Hayden, Karrasch, Kerr, Kreisel, Murphy, Nenci, Neurath, Nolan, O'Connor, Ota, Rakoff-Nahoum, Schreiber, Schwarz, Steinbrecher, Tambuwala, Tao, Vereecke, Wullaert, Zenewicz, Zhang   +26 more
core   +1 more source

Early diagnostic value of Bcl-3 localization in colorectal cancer [PDF]

, 2015
B-cell leukemia 3 (Bcl-3) is a member of the inhibitor of κB family, which regulates a wide range of biological processes by functioning as a transcriptional activator or as a repressor of target genes. Elevated expression, sustained nuclear accumulation,
Göran Landberg, Karin Jirström, Karunakar Saamarthy, Katarzyna Chmielarska Masoumi, Martin Johansson, Ramin Massoumi, Sofie Björner   +6 more
core   +1 more source