Results 51 to 60 of about 202,367 (202)

Mitochondrial targeting of the pro-apoptotic protein Bax : Role of the Bax carboxy-terminal tail. [PDF]

open access: yes, 2009
Here, I address the function of the carboxy-terminal hydrophobic helix of the pro-apoptotic protein Bax. There has been considerable controversy as to whether this sequence is required for the targeting and insertion of Bax into the mitochondrial outer ...
Brock, Stephanie Erin, 1980-
core   +1 more source

Association of Bax expression and Bcl2/Bax ratio with clinical and molecular prognostic markers in chronic lymphocytic leukemia [PDF]

open access: yesJournal of Medical Biochemistry, 2016
Background: In chronic lymphocytic leukemia (CLL), in vivo apoptotic resistance of malignant B lymphocytes results, in part, from the intrinsic defects of their apoptotic machinery.
Vučićević Ksenija   +8 more
doaj  

Estudo do efeito neuroprotetor da mirtazapina e imipramina e sua relação com a expressão gênica de proteínas apoptóticas [PDF]

open access: yes, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Neurociências.Neste estudo foram investigados a ação neuroprotetora dos antidepressivos mirtazapina e imipramina e os efeitos ...
Lieberknecht, Vicente
core  

RACK1 promotes Bax oligomerization and dissociates the interaction of Bax and Bcl-XL

open access: yes, 2010
Bax, a member of Bcl-2 family, plays an essential role in apoptotic pathways induced by a number of apoptotic stimulus. In a search for new potential binding partners of Bax, we identified the receptor for activated C-kinase 1 (RACK1) by a yeast two ...
Zhang, Liying   +17 more
core   +1 more source

Effect of high-intensity interval training on expression of pro and anti-apoptotic genes in myocard tissue of aged male C57BL/6 mice [PDF]

open access: yesفیزیولوژی ورزش و فعالیت بدنی, 2019
Purpose: Bax and BCL-2 genes are important genes that involve in the intrinsic pathway of apoptosis. Although the effects of interval and intensive exercises on the mechanisms involved in the gaining processes are less considered.
Rahman Soori   +3 more
doaj   +1 more source

The peculiarities of eosinophil apoptosis damage in patients with severe therapy-resistant bronchial asthma

open access: yesБюллетень сибирской медицины, 2005
The study aim: to investigate the dynamics of transcription factor p53, proapoptoic (bax, bcl-XS), antiapoptotic (bcl-2, bcl-XL) effectors, IL-5 expression in peripheral blood eosinophils of patients with severe therapy-resistant bronchial asthma (BA ...
L. Yu. Nikitina   +3 more
doaj   +1 more source

Delineating the Steps of BAX Pore Activation [PDF]

open access: yes, 2011
The BCL2 protein family is the primary gatekeeper of mitochondrial apoptosis and governs integrity of the organelles\u27 outer membranes. Permeabilization of mitochondrial outer membranes permits egress of cytochrome c and other apoptogenic factors ...
Christenson, Eric
core   +1 more source

Solo show, Cavalcade, BoLee and Workman, Bruton

open access: yes
Cavalcade is a solo exhibition of new work by artist Olivia Bax. Situated in a former Methodist church, the sculptures respond to the space’s distinctive architecture.
BoLee and Workman, Bax, Olivia
core   +2 more sources

BAX and BAK mediate nitric oxide-indeced cell death.

open access: yes, 2013
Bax−/−/Bak−/− MEFs were infected with either Bax, Bak or GFP as a control. BAX and BAK expression was verified by Western analysis (A,B). Bax−/−/Bak−/− MEFs expressing GFP, BAK or BAX were treated with 0, 100, 200 and 400 µM DETA-NO for 48 hours and cell
Emelyn H. Shroff (163459)   +3 more
core   +1 more source

Bax regulates neuronal Ca2+ homeostasis [PDF]

open access: yes, 2015
Excessive Ca(2+) entry during glutamate receptor overactivation ("excitotoxicity") induces acute or delayed neuronal death. We report here that deficiency in bax exerted broad neuroprotection against excitotoxic injury and oxygen/glucose deprivation in ...
Heiko Duessmann (7897355)   +10 more
core   +3 more sources

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