Results 221 to 230 of about 203,854 (298)

Anti-bladder cancer effects of nuciferine, a bioactive compound extracted from <i>Nelumbo nucifera</i> leaves. [PDF]

Front Nutr
Qin B, Liang H, Kuang T, Wei C, Qin M, Li J, Lu H, Guo C.   +7 more
europepmc   +1 more source

Brassinin Inhibits Cell Survival and Autophagy via Modulation of ROS Production and the AMPKα‐beclin1 Signaling Pathway in Gliomas

Phytotherapy Research, EarlyView.
Brassinin, a phytoalexin derived primarily from Chinese cabbage, exhibits potent anticancer activity against glioblastoma (GBM). Mechanistically, brassinin treatment elevates intracellular ROS levels in GBM cells, triggering two parallel outcomes: (i) direct induction of apoptosis, and (ii) suppression of cytoprotective autophagy through downregulation
Sunil Rauniyar, Yuhui Wang, Qiaoshan Zhang, Shicheng Zhang, Jiale Yin, Tong Zhang, Shangfeng Gao, Rutong Yu   +7 more
wiley   +1 more source

Restoration of PPD-Induced Injury in iHDPCs via the OS-Mitochondrial Apoptosis Pathway: Screening and Validation of Natural Compounds. [PDF]

Int J Mol Sci
Ren Y, He J, Zheng L, Yue L, He C, Huang D, Zhang F.   +6 more
europepmc   +1 more source

Multitarget Regulatory Mechanisms and Research Advances of Plant‐Derived Bioactive Ingredients in Hypertension Prevention and Management

Phytotherapy Research, EarlyView.
Schematic overview of the multi‐target and multi‐pathway mechanisms of PDBI in the prevention and management of hypertension. ABSTRACT Hypertension remains a major global risk factor for cardiovascular diseases, yet current treatments face challenges such as suboptimal blood pressure control and inadequate organ protection.
Qiqi Deng, Yonglin Zhang, Jing Pan, Jing Luo, Hualin Sun, Chaonian Li, Li Li   +6 more
wiley   +1 more source

Shikonin combined with curcumin synergistically induces apoptosis of glioma cells by inhibiting the PI3K/Akt/NF-κB signaling pathway. [PDF]

Oncol Lett
Zhao X, Zhang M, He Y, Yu Z, Sun Y, Zhu J.   +5 more
europepmc   +1 more source

Ruta graveolens L. in Evidence‐Based Phytotherapy: Pharmacological Activities, Bioactive Compounds and Safety

Phytotherapy Research, EarlyView.
Graphical representation of ethnomedical uses, major bioactive compounds, pharmacological potential and toxicological risks of Ruta graveolens L. ABSTRACT Ruta graveolens L. is widely used in traditional European, Asian, African, and South American medicine for digestive, nervous, cardiovascular, respiratory, and reproductive disorders.
Tetiana Serhiienko, Victoriya Georgiyants, Liudas Ivanauskas, Olha Mykhailenko   +3 more
wiley   +1 more source

Identification of a postnatal period of interdependent neurogenesis and apoptosis in peripheral neurons

Biology Open
Catherine L. Kaminski, Debarghya Dutta Banik, Ligia B. Schmitd, Brian A. Pierchala   +3 more
doaj   +1 more source

PTEN-L inhibits mitophagy and GSDME-dependent pyroptosis via Parkin dephosphorylation. [PDF]

EMBO Rep
Yan C, Huang C, Liu X, Liu Y, Tang Y, Zhu Z, Qi J, Guo H, Li Y, Zhu Y, Wang L, Luo Y, Xing L, Wang H, Li F, Sun B, Liu S, Lu G, Xu H, Zhou B, Shen HM, Wang L.   +21 more
europepmc   +1 more source

Salvianolic Acid C Protects Against Hepatic Ischemia–Reperfusion Injury via Heat Shock Protein 90α‐Mediated Activation of the Phosphatidylinositol 3‐Kinase/Protein Kinase B Signaling Pathway

Phytotherapy Research, EarlyView.
Salvianolic acid C (SaC) protects against hepatic ischemia–reperfusion injury (HIRI) by upregulating HSP90α and activating the PI3K/AKT pathway, thereby alleviating oxidative stress, inflammation, apoptosis, and necrosis. ABSTRACT Hepatic ischemia–reperfusion injury (HIRI) is a major challenge in liver surgery, and effective pharmacological ...
Pingping Qiao, Alimu Tulahong, Xinlu Xu, Tiemin Jiang, Ruiqing Zhang, Yanze Lin, Zhongdian Yuan, Rexiati Ruze, Yingmei Shao   +8 more
wiley   +1 more source

Sinensetin Induces Oxidative Stress-Mediated Apoptosis in Non-Small Cell Lung Cancer Cells by Suppressing Nrf2/ARE-Dependent Antioxidant Defense. [PDF]

J Biochem Mol Toxicol
Li J, He R, He J, Ye J, Xie Y, Yuan B.
europepmc   +1 more source