Results 91 to 100 of about 202,367 (202)
CWP release from ESVs is Bax specific.
A) ESVs in encysting Bax-expressing cells treated with the membrane-permeable Bax-inhibiting peptide Ku70 are at least partially protected. Note the co-localization of Bax (green) with (partially intact) ESVs and significantly less cytoplasmic or ...
Adrian B. Hehl (74036) +3 more
core +1 more source
Greasing the path to BAX/BAK activation
BAX/BAK activation leading to mitochondrial outer-membrane permeabilization is a key commitment point in apoptosis. Chipuk et al. now identify two sphingolipids as specific cofactors for BAX/BAK activation that lower the threshold for apoptosis ...
MARTIN, SEAMUS
core +1 more source
Immunohistochemical analysis of BAX and BAK expression in malignant mesothelioma patients.
A) Representative image of normal tissue control and positive tissues stained for BAX and BAK by immunohistochemisty. B) Pie-charts representing the frequency of BAX, BAK and BAX-BAK negativity in previously treated 30 mesothelioma patients.
Vignesh K. Gunasekharan (419362) +10 more
core +1 more source
Molecular and Anticancer Effects of β-Carotene on the Apoptotic Pathway via Regulation of Bax/Bcl-2 in MCF-7 Breast Cancer Cell Line [PDF]
Introduction: Breast cancer stands out as the top cancer type and a major reason for cancer deaths in women around the world. New studies point to β-carotene having possible healing impacts on this cancer.
Amineh Majidi +2 more
doaj
Objectives: to compare the expression of Bcl-2, Bax and Bcl-2/Bax ratio in cumulus cell and oocyte between vitrified oocyte pre and post in vitro maturation.Materials and Methods: Maturation was operated in medium TC 100 µl for 24 hours.
Haryanto Aswin +2 more
core +1 more source
Effect of Oocyte Vitrification Before and After in Vitro Maturation Towards Bcl-2, Bax and Bcl-2/Bax Ratio Expression [PDF]
Objectives: to compare the expression of Bcl-2, Bax and Bcl-2/Bax ratio in cumulus cell and oocyte between vitrified oocyte pre and post in vitro maturation.Materials and Methods: Maturation was operated in medium TC 100 µl for 24 hours.
Faizah, Z. (Zakiyatul) +2 more
core
Examination of the apelin signaling pathway in acetaminophen-induced hepatotoxicity in rats
The present study identifies the level changes of markers (Apelin, Elabela, Meteorin, ALT, AST, GGT) in the liver after acute intake of high-dose paracetamol and their role in determining liver damage.
Dolanbay Turgut +4 more
doaj +1 more source
目的通过建立小鼠原位肝癌模型,给予化癥散积颗粒灌胃,探讨其对小鼠原位肝癌Bcl-2/Bax表达的影响。方法将H22瘤株直接注射到肝脏的方法建立小鼠原位肝癌模型;分组:模型组、阳性对照组、化癥散积颗粒高、中、低剂量组;采用TUNEL染色法检测凋亡细胞;RT-PCR和Western-Blot分别检测肿瘤组织Bcl-2和Bax mRNA和蛋白表达差异。结果 阳性对照组(又称斑蝥组)和中、高剂量组中药可以诱导肝癌细胞发生凋亡;可以显著增加肿瘤组织中Bax ...
金学洙 +4 more
doaj
Elucidating the mechanism of anti-apoptotic activity of α-crystallin and its therapeutic potential [PDF]
α- Crystallins are the structural proteins of the eye lens which possess anti-apoptotic activity. Both αA- and αB- crystallins are distinct antiapoptotic regulators which can interact with Bax and Bcl-XS, proapoptotic members of the Bcl-2 family in order
Aparajita Chakraborty +2 more
doaj

