Developmental Dynamics, EarlyView.Abstract Background Elp1, a subunit of the Elongator complex, is essential for tRNA modification and neuronal development. Mutations in ELP1 underlie familial dysautonomia (FD), a disorder marked by sensory and autonomic neuropathy. While loss of Elp1 disrupts trigeminal ganglion formation and survival, the downstream molecular consequences remain ...
Carrie E. Leonard +3 more
wiley +1 more source
Терапевтический архив, 2011 Aim. To determine unbalance in the system of programmed cell death in the cells CD34+ of the bone marrow (BM) and peripheral blood (PB) before and after cytostatic impact in acute leukemia (AL). Material and methods.
Elena Evgen'evna Khodunova +11 more
doaj
Involment of p53, Bax, and Bcl-2 Pathway in Microcystins-Induced Apoptosis in Rat Testis
, 2011 It has been reported that microcystins (MCs) could accumulate in the gonads of mammals and MCs exposure exerts obvious toxic effects on male reproductive system of mammals.
xieping@ihb.ac.cn +7 more
core
Sacubitril/valsartan preserves regional cardiac function following myocardial infarction in rats
ESC Heart Failure, Volume 12, Issue 2, Page 1304-1315, April 2025.Parts of the figure were drawn by using pictures from Servier Medical Art. Servier Medical Art by Servier is licensed under a Creative Commons Attribution 3.0 Unported License (https://creativecommons.org/licenses/by/3.0/). Abstract Aims Sacubitril/valsartan (Sac/Val) is used for treatment of heart failure. The effect of Sac/Val on regional dysfunction
Einar Sjaastad Nordén +16 more
wiley +1 more source
Annona squamosa: Phytochemical Fingerprinting, Health‐Improving Traits, and Functional Applications
Food Chemistry International, EarlyView.Annona squamosa (custard apple) is a nutrient‐rich fruit containing diverse bioactive phytochemicals (e.g., acetogenins, flavonoids, and alkaloids) that contribute to multiple health benefits, including antioxidant, antihyperlipidemic, and antimicrobial activities, highlighting its potential as a functional food and medicinal resource.
Mohamed Fawzy Ramadan +4 more
wiley +1 more source
Extended In Vitro Maturation Reveals a Prolonged Nuclear Maturation Window and Dynamic BAX/BCL-2 Regulation in Dromedary Camel Oocytes. [PDF]
Vet SciAlhobish WH, Al-Ghadi MQ, Alyami NM.
europepmc +1 more source
Flavour and Fragrance Journal, EarlyView.Phytochemistry and biopotential of Melia azedarach Linn. ABSTRACT Melia azedarach Linn. (chinaberry), a medicinal plant native to tropical Asia, is a rich source of diverse bioactive compounds with reported pharmacological activities and promising therapeutic potential.
Priya Chand +3 more
wiley +1 more source
Immunohistochemical Expression of M30, BCL-2, BAX, and Ki-67 in Pancreatic Ductal Adenocarcinoma: Association with Clinicopathological Features. [PDF]
Diagnostics (Basel)Demirciler Yavaş B, Yılmaz S.
europepmc +1 more source
Hydrogel‐Based Bioelectronics: From Therapy and Sensing to Neuromorphic Computation
FlexTech, EarlyView.This review establishes a material–conduction–property–application framework connecting hydrogel chemistry and charge transport with therapy, sensing, closed‐loop feedback, and neuromorphic computation. ABSTRACT Bioelectronics establish bidirectional communication between living systems and electronic devices, providing an enabling platform for ...
Jianlong Hong +7 more
wiley +1 more source
Cycloastragenol Attenuates Cisplatin-Induced Ovarian Toxicity in Rats: Associations With TERT Expression, Apoptotic Balance, and FOXO3a-mTOR-Related Signaling. [PDF]
J Biochem Mol ToxicolErol GNA, Yar AS, Kaplanoğlu GT.
europepmc +1 more source