Results 91 to 100 of about 202,367 (202)

CWP release from ESVs is Bax specific.

open access: yes, 2013
A) ESVs in encysting Bax-expressing cells treated with the membrane-permeable Bax-inhibiting peptide Ku70 are at least partially protected. Note the co-localization of Bax (green) with (partially intact) ESVs and significantly less cytoplasmic or ...
Adrian B. Hehl (74036)   +3 more
core   +1 more source

Greasing the path to BAX/BAK activation

open access: yes, 2012
BAX/BAK activation leading to mitochondrial outer-membrane permeabilization is a key commitment point in apoptosis. Chipuk et al. now identify two sphingolipids as specific cofactors for BAX/BAK activation that lower the threshold for apoptosis ...
MARTIN, SEAMUS
core   +1 more source

Immunohistochemical analysis of BAX and BAK expression in malignant mesothelioma patients.

open access: yes, 2013
A) Representative image of normal tissue control and positive tissues stained for BAX and BAK by immunohistochemisty. B) Pie-charts representing the frequency of BAX, BAK and BAX-BAK negativity in previously treated 30 mesothelioma patients.
Vignesh K. Gunasekharan (419362)   +10 more
core   +1 more source

Molecular and Anticancer Effects of β-Carotene on the Apoptotic Pathway via Regulation of Bax/Bcl-2 in MCF-7 Breast Cancer Cell Line [PDF]

open access: yesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām
Introduction:  Breast cancer stands out as the top cancer type and a major reason for cancer deaths in women around the world. New studies point to β-carotene having possible healing impacts on this cancer.
Amineh Majidi   +2 more
doaj  

Effect of oocyte vitrification before and after in vitro maturation towards Bcl-2, Bax and Bcl-2/Bax ratio expression

open access: yes, 2017
Objectives: to compare the expression of Bcl-2, Bax and Bcl-2/Bax ratio in cumulus cell and oocyte between vitrified oocyte pre and post in vitro maturation.Materials and Methods: Maturation was operated in medium TC 100 µl for 24 hours.
Haryanto Aswin   +2 more
core   +1 more source

Effect of Oocyte Vitrification Before and After in Vitro Maturation Towards Bcl-2, Bax and Bcl-2/Bax Ratio Expression [PDF]

open access: yes, 2016
Objectives: to compare the expression of Bcl-2, Bax and Bcl-2/Bax ratio in cumulus cell and oocyte between vitrified oocyte pre and post in vitro maturation.Materials and Methods: Maturation was operated in medium TC 100 µl for 24 hours.
Faizah, Z. (Zakiyatul)   +2 more
core  

Examination of the apelin signaling pathway in acetaminophen-induced hepatotoxicity in rats

open access: yesTürk Biyokimya Dergisi
The present study identifies the level changes of markers (Apelin, Elabela, Meteorin, ALT, AST, GGT) in the liver after acute intake of high-dose paracetamol and their role in determining liver damage.
Dolanbay Turgut   +4 more
doaj   +1 more source

化癥散积颗粒对小鼠原位肝癌Bcl-2/Bax表达的影响

open access: yesZhongguo shiyan zhenduanxue, 2012
目的通过建立小鼠原位肝癌模型,给予化癥散积颗粒灌胃,探讨其对小鼠原位肝癌Bcl-2/Bax表达的影响。方法将H22瘤株直接注射到肝脏的方法建立小鼠原位肝癌模型;分组:模型组、阳性对照组、化癥散积颗粒高、中、低剂量组;采用TUNEL染色法检测凋亡细胞;RT-PCR和Western-Blot分别检测肿瘤组织Bcl-2和Bax mRNA和蛋白表达差异。结果 阳性对照组(又称斑蝥组)和中、高剂量组中药可以诱导肝癌细胞发生凋亡;可以显著增加肿瘤组织中Bax ...
金学洙   +4 more
doaj  

Cytosolic Bax [PDF]

open access: yesJournal of Biological Chemistry, 2012
Sandra Vogel   +6 more
openaire   +1 more source

Elucidating the mechanism of anti-apoptotic activity of α-crystallin and its therapeutic potential [PDF]

open access: yesJournal of Stress Physiology & Biochemistry
α- Crystallins are the structural proteins of the eye lens which possess anti-apoptotic activity. Both αA- and αB- crystallins are distinct antiapoptotic regulators which can interact with Bax and Bcl-XS, proapoptotic members of the Bcl-2 family in order
Aparajita Chakraborty   +2 more
doaj  

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