Results 131 to 140 of about 203,854 (298)

Examination of the apelin signaling pathway in acetaminophen-induced hepatotoxicity in rats

open access: yesTürk Biyokimya Dergisi
The present study identifies the level changes of markers (Apelin, Elabela, Meteorin, ALT, AST, GGT) in the liver after acute intake of high-dose paracetamol and their role in determining liver damage.
Dolanbay Turgut   +4 more
doaj   +1 more source

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

open access: yesBMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen   +9 more
wiley   +1 more source

化癥散积颗粒对小鼠原位肝癌Bcl-2/Bax表达的影响

open access: yesZhongguo shiyan zhenduanxue, 2012
目的通过建立小鼠原位肝癌模型,给予化癥散积颗粒灌胃,探讨其对小鼠原位肝癌Bcl-2/Bax表达的影响。方法将H22瘤株直接注射到肝脏的方法建立小鼠原位肝癌模型;分组:模型组、阳性对照组、化癥散积颗粒高、中、低剂量组;采用TUNEL染色法检测凋亡细胞;RT-PCR和Western-Blot分别检测肿瘤组织Bcl-2和Bax mRNA和蛋白表达差异。结果 阳性对照组(又称斑蝥组)和中、高剂量组中药可以诱导肝癌细胞发生凋亡;可以显著增加肿瘤组织中Bax ...
金学洙   +4 more
doaj  

Diversity, Inclusion, and Firm Performance: The Corporate Innovation Channel

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT This paper examines whether corporate innovation—measured both as general innovative output and as environmental innovation—mediates the relationship between diversity and inclusion (D&I) and corporate financial performance (CFP). Prior research has documented positive, negative, and null associations between D&I and financial outcomes, but ...
Eleonora Monaco   +3 more
wiley   +1 more source

Elucidating the mechanism of anti-apoptotic activity of α-crystallin and its therapeutic potential [PDF]

open access: yesJournal of Stress Physiology & Biochemistry
α- Crystallins are the structural proteins of the eye lens which possess anti-apoptotic activity. Both αA- and αB- crystallins are distinct antiapoptotic regulators which can interact with Bax and Bcl-XS, proapoptotic members of the Bcl-2 family in order
Aparajita Chakraborty   +2 more
doaj  

Cytosolic Bax [PDF]

open access: yesJournal of Biological Chemistry, 2012
Sandra Vogel   +6 more
openaire   +1 more source

Tail Risk and Earnings Management: The Role of Gender Diversity and Environmental–Social Reporting in International Banking

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT We examine the impacts of earnings management on the tail risks of banks using a dataset of 3297 bank‐year observations across 157 publicly traded commercial banks from 12 countries, covering 2002–2022. Our findings suggest that banks engaging in earnings management activities exhibit higher tail risks.
Marwa Elnahass   +3 more
wiley   +1 more source

脑缺血再灌注糖尿病大鼠海马CA1区凋亡基因的表达

open access: yesZhongguo shiyan zhenduanxue, 2007
目的观察凋亡基因Bcl-2、Bax在糖尿病大鼠脑缺血再灌注海马CA1区神经元损伤中的表达。方法采用链脲佐菌素(STZ)诱导和线栓法制备糖尿病大脑中动脉闭塞模型(MCAO),应用HE染色和免疫组化方法比较糖尿病脑缺血再灌注组与缺血再灌注组海马CA1区神经元缺失、凋亡基因Bcl-2、Bax的表达。结果糖尿病脑缺血再灌注组海马CA1区神经元缺失,明显高于缺血再灌注组 ...
张季声   +7 more
doaj  

Recent Progress of Biomass‐Derived Nitrogen‐Doped Carbon Materials as Electrocatalysts: Carbonization, Functionalization, and Applications

open access: yesCarbon Energy, EarlyView.
Integrating renewable energy with electrochemical conversion and storage is crucial for sustainable energy solutions. Nitrogen‐doped biomass‐derived carbon materials have emerged as effective catalysts for key reactions such as ORR, HER, and CO2RR. This review explores their synthesis, functionalization, characterization, and catalytic applications ...
Shilong Fu   +3 more
wiley   +1 more source

Economic Profitability of ESG Investments in the Wine Sector: A Bibliometric Systematic Literature Review

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study examines whether and under which conditions ESG investments are associated with profitability in the wine sector. A PRISMA‐guided bibliometric–systematic review of 83 peer‐reviewed articles from Scopus and Web of Science combines bibliometric mapping, qualitative synthesis, and MMAT‐based quality appraisal.
Niccolò Lombardi
wiley   +1 more source

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