lncRNA PCA3 plays a key role in colon cancer occurrence and development. [PDF]
Arch Med SciPan Y, Zhu L, Pu J, Wang W, Qian W.
europepmc +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Aspartyl‐tRNA synthetase 2 (DARS2), the mitochondrial enzyme responsible for aminoacylation of aspartyl‐tRNA, is traditionally known for its effect on protein synthesis. Recently, DARS2 is reported to be implicated in tumorigenesis. However, its specific effect on breast cancer (BC) is poorly understood.
Na Wang, Ming Huang
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Hypotonicity-Induced WNK1 Phosphorylation Prevents H<sub>2</sub>O<sub>2</sub>-Induced Apoptosis in Vascular Smooth Muscle Cells. [PDF]
Basic Clin Pharmacol ToxicolZhang Y +11 more
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The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Pediatric acute lung injury (ALI) is a life‐threatening syndrome defined by dysregulated pulmonary inflammation and impaired alveolar gas exchange, with limited therapeutic interventions. This study aims to evaluate the therapeutic efficacy and mechanistic basis of Olaparib, a clinically approved PARP inhibitor, using in vitro and in vivo ...
Fen Gong +5 more
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Metformin potentiates arsenic disulfide in diffuse large B-cell lymphoma: modulation of BAX/BCL-2 apoptotic pathway and hedgehog pathway. [PDF]
Front OncolZhang J +5 more
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The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Tongue squamous cell carcinoma, the most aggressive subtype of oral squamous cell carcinoma, which is associated with high mortality, frequent recurrence, and early lymph‐node metastasis. Triptolide, a bioactive diterpenoid from Tripterygium wilfordii, exhibits broad anticancer activity.
Shan‐Shan Wang +3 more
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Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research
Mass Spectrometry Reviews, EarlyView.Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik +3 more
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Evaluation of the protective effects of green tea for ischemia-reperfusion injury in rat ovary tissue: an experimental study. [PDF]
Acta Cir BrasDogru HY +3 more
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Prevention of Early Onset of Breast Cancer With Ashwagandha
Molecular Carcinogenesis, EarlyView.ABSTRACT Prevention of breast cancer is feasible because many risk factors for this malignancy are known (e.g., family history, reproductive factors, etc.). Medicinal plants and/or their bioactive phytochemicals are attractive for the prevention of early onset of breast cancer due to their generally favorable safety profile.
Eun‐Ryeong Hahm +2 more
wiley +1 more source
Transcriptomic Profiling of Oxidative Stress-Associated Immune and Apoptotic Signatures and In Silico Prediction of Therapeutic Candidates for Sjögren's Syndrome Dry Eye. [PDF]
BiomedicinesWang J +8 more
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