Results 31 to 40 of about 11,024,551 (300)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Advances in Materials Science and Engineering, 2016 Sulfur retention ability of Bayer red mud from alumina plant was investigated. Bayer red mud modified by fusel salt and waste mother liquor of sodium ferrocyanide as the main sulfur fixation agent and the calcium based natural mineral materials as ...
Yang Liu +4 more
doaj +1 more source
Optimisation of the Operation of an Industrial Power Plant under Steam Demand Uncertainty
Energies, 2021 The operation of on-site power plants in the chemical industry is typically determined by the steam demand of the production plants. This demand is uncertain due to deviations from the production plan and fluctuations in the operation of the plants.
Keivan Rahimi-Adli +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Nature CommunicationsCrystal polymorphism is an important and fascinating aspect of solid state chemistry with far reaching implications in the pharmaceuticals, agrisciences, nutraceuticals, battery and aviation industries.
Dong Zhou +10 more
doaj +1 more source
Solution chemistry of some dicarboxylate salts of relevance to the Bayer process [PDF]
, 2001 These ions are either significant impurities in the concentrated alkaline aluminate solutions used in the Bayer process for the purification of alumina, or are useful models for degraded organic matter in industrial Bayer liquors.
Tromans, Andrew John
core
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Artificial neural network prediction of the aluminum extraction from bauxite in the Bayer process [PDF]
Journal of the Serbian Chemical Society, 2012 This paper presents the results of statistical modeling of the bauxite leaching process, as part of Bayer technology for an alumina production.
Đurić Isidora +2 more
doaj +1 more source
Pharmaceutics, 2021 The drying unit of a continuous from-powder-to-tablet manufacturing line based on twin-screw granulation (TSG) is a crucial intermediate process step to achieve the desired tablet quality.
Alexander Ryckaert +6 more
doaj +1 more source