Results 51 to 60 of about 212,322 (298)

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

A New Class of Bayes Minimax Estimators of the Mean Matrix of a Matrix Variate Normal Distribution

Mathematics
Bayes minimax estimation is important because it provides a robust approach to statistical estimation that considers the worst-case scenario while incorporating prior knowledge.
Shokofeh Zinodiny, Saralees Nadarajah
doaj   +1 more source

Some bayes estimation startegies in exponential distribution under a weighted loss function [PDF]

Journal of Hyperstructures, 2018
In Bayesian approach, prior knowledge is often vague and any elicited prior distribution is only an approximation to the true one. E-Bayes and robust Bayes approaches consider a class of prior distributions instead of a single prior.
A. Kiapour, mehran naghizadeh qomi
doaj   +1 more source

Discriminant analysis of the equicorrelated Gaussian observations

Lietuvos Matematikos Rinkinys, 2021
In this paper the problem of classification of an observation into one of two Gaussian populations with different means and common variance is considered in the case when equicorrelated training sample is given.
Kęstutis Dučinskas, Jurgita Neverdauskaiė   +1 more
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Estimation of the Rayleigh Distribution under Unified Hybrid Censoring

Austrian Journal of Statistics, 2021
We derive some estimators of the scale parameter of the Rayleigh distribution under the unified hybrid censoring scheme. We also derive some estimators of the reliability function and the entropy of the Rayleigh distribution. First, we obtain the maximum
Young Eun Jeon, Suk-Bok Kang
doaj   +1 more source

On Inconsistent Bayes Estimates of Location

The Annals of Statistics, 1986
This paper is related to the authors paper ibid. 14, 1-26 (1986; see the foregoing review, Zbl 0595.62022). In some relatively natural settings, Bayes estimates of location are shown to be inconsistent.
Diaconis, P., Freedman, D.
openaire   +3 more sources

A Bayes Linear Bayes Method for Estimation of Correlated Event Rates [PDF]

Risk Analysis, 2013
Typically, full Bayesian estimation of correlated event rates can be computationally challenging since estimators are intractable. When estimation of event rates represents one activity within a larger modeling process, there is an incentive to develop more efficient inference than provided by a full Bayesian model.
Quigley, John, Wilson, Kevin, Walls, Lesley, Bedford, Tim   +3 more
openaire   +4 more sources

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source