Results 51 to 60 of about 6,694 (263)
Discriminant analysis of the equicorrelated Gaussian observations
In this paper the problem of classification of an observation into one of two Gaussian populations with different means and common variance is considered in the case when equicorrelated training sample is given.
Kęstutis Dučinskas +1 more
doaj +1 more source
On Inconsistent Bayes Estimates of Location
This paper is related to the authors paper ibid. 14, 1-26 (1986; see the foregoing review, Zbl 0595.62022). In some relatively natural settings, Bayes estimates of location are shown to be inconsistent.
Diaconis, P., Freedman, D.
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This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Estimation of the Rayleigh Distribution under Unified Hybrid Censoring
We derive some estimators of the scale parameter of the Rayleigh distribution under the unified hybrid censoring scheme. We also derive some estimators of the reliability function and the entropy of the Rayleigh distribution. First, we obtain the maximum
Young Eun Jeon, Suk-Bok Kang
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A Bayes Linear Bayes Method for Estimation of Correlated Event Rates [PDF]
Typically, full Bayesian estimation of correlated event rates can be computationally challenging since estimators are intractable. When estimation of event rates represents one activity within a larger modeling process, there is an incentive to develop more efficient inference than provided by a full Bayesian model.
Quigley, John +3 more
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Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
AbstractIn this paper the author tries to give general conditions for the existence of Bayes estimates and for the consistency of sequences of Bayes estimates.In Section 3 we prove existence theorems for Bayes estimates, which contain those of DeGroot and Rao [3], as a special case.
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We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Bayesian and E-Bayesian Estimation for Odd Generalized Exponential Inverted Weibull Distribution [PDF]
Lifetime distributions under Type-II censored scheme have been attracting great interest due to their wide application in the fields of science, reliability, economics, environmental sciences, finance, engineering, social sciences, medicine and other ...
A. A. Mohamed +2 more
doaj +1 more source

