Results 51 to 60 of about 128,009 (300)

On the use of non-local prior densities in Bayesian hypothesis tests [PDF]

open access: yes, 2010
We examine philosophical problems and sampling deficiencies that are associated with current Bayesian hypothesis testing methodology, paying particular attention to objective Bayes methodology.
Valen E. Johnson   +4 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

From Empirical Bayes to Full Bayes: Methods for Analysing Traffice Safety Data, October 25, 2004 [PDF]

open access: yes, 2004
Traffic safety engineers are among the early adopters of Bayesian statistical tools for analyzing crash data. As in many other areas of application, empirical Bayes methods were their first choice, perhaps because they represent an intuitively ...

core  

Bayes Factors for Partially Observed Stochastic Epidemic Models [PDF]

open access: yes, 2019
We consider the problem of model choice for stochastic epidemic models given partial observation of a disease outbreak through time. Our main focus is on the use of Bayes factors.
Alharthi, Muteb   +2 more
core   +1 more source

Bayesian Estimation Based on Progressively Type-II Censored Samples from Compound Rayleigh Distribution [PDF]

open access: yesJournal of Statistical Theory and Applications (JSTA), 2015
This paper considers inference under progressive type-II censoring scheme with a compound Rayleigh failure time distribution. The maximum likelihood (ML) and the Bayes estimators for the two unknown parameters of the compound Rayleigh distribution (CRD ...
Rashad Mohamed EL-Sagheer   +1 more
doaj   +1 more source

Comparing Fuzzy Logic Mamdani and Naïve Bayes for Dental Disease Detection

open access: yesJournal of Information Systems Engineering and Business Intelligence, 2022
Background: Dental disease detection is essential for the diagnosis of dental diseases. Objective: This research compares the Mamdani fuzzy logic and Naïve Bayes in detecting dental diseases.
Linda Perdana Wanti, Oman Somantri
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Multivariate reliability modelling with empirical Bayes inference [PDF]

open access: yes, 2007
Recent developments in technology permit detailed descriptions of system performance to be collected and stored. Consequently, more data are available about the occurrence, or non-occurrence, of events across a range of classes through time.
Quigley, J.L., Walls, L.A.
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

From Empirical Bayes to Full Bayes: Methods for Analyzubg Traffic Safey Data, October 25, 2004 [PDF]

open access: yes, 2004
Traffic safety engineers are among the early adopters of Bayesian statistical tools for analyzing crash data. As in many other areas of application, empirical Bayes methods were their first choice, perhaps because they represent an intuitively ...

core  

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