Results 61 to 70 of about 9,437,008 (290)

Loss-Driven Bayesian Active Learning

open access: yesCoRR
The central goal of active learning is to gather data that maximises downstream predictive performance, but popular approaches have limited flexibility in customising this data acquisition to different downstream problems and losses. We propose a rigorous loss-driven approach to Bayesian active learning that allows data acquisition to directly target ...
Zhuoyue, H   +2 more
openaire   +4 more sources

Accelerating Dental Adhesive Innovations Through Active Learning and Bayesian Optimization [PDF]

open access: yes
The discovery of new dental materials is typically a slow process due to high-dimensionality of the formulation space as well as the multiple competing objectives which must be optimized for a given application.
Ramsey, Issa   +2 more
core   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Bayesian Active Learning for Sensitivity Analysis [PDF]

open access: yes, 2006
Designs of micro electro-mechanical devices need to be robust against fluctuations in mass production. Computer experiments with tens of parameters are used to explore the behavior of the system, and to compute sensitivity measures as expectations over the input distribution.
openaire   +2 more sources

Bayesian Active Learning for Classification and Preference Learning

open access: yesCoRR, 2011
Information theoretic active learning has been widely studied for probabilistic models. For simple regression an optimal myopic policy is easily tractable. However, for other tasks and with more complex models, such as classification with nonparametric models, the optimal solution is harder to compute.
Neil Houlsby   +3 more
openaire   +3 more sources

Active Structure Learning of Bayesian Networks in an Observational Setting

open access: yesCoRR, 2021
We study active structure learning of Bayesian networks in an observational setting, in which there are external limitations on the number of variable values that can be observed from the same sample. Random samples are drawn from the joint distribution of the network variables, and the algorithm iteratively selects which variables to observe in the ...
Noa Ben-David, Sivan Sabato
openaire   +5 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

BATMAN: BAyesian Target Modelling for Active iNference

open access: yes, 2020
Active Inference is an emerging framework for designing intelligent agents. In an Active Inference setting, any task is formulated as a variational free energy minimisation problem on a generative probabilistic model.
Koudahl, Magnus, de Vries, A. (Bert)
core   +1 more source

Bayesian Active Learning By Distribution Disagreement

open access: yesCoRR
Active Learning (AL) for regression has been systematically under-researched due to the increased difficulty of measuring uncertainty in regression models. Since normalizing flows offer a full predictive distribution instead of a point forecast, they facilitate direct usage of known heuristics for AL like Entropy or Least-Confident sampling.
Thorben Werner, Lars Schmidt-Thieme
openaire   +2 more sources

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi   +17 more
wiley   +1 more source

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