Results 181 to 190 of about 2,193,761 (259)

Re‐evaluating impaired consciousness in temporal lobe epilepsy: The role of language dominance and network reorganization

open access: yesEpilepsia, EarlyView.
Abstract Objective Temporal lobe epilepsy (TLE) frequently affects clinically‐classified ictal consciousness, which the 2025 International League Against Epilepsy (ILAE) classification operationalizes through clinical assessment of awareness and responsiveness.
Radheshyam Stepponat   +8 more
wiley   +1 more source

Limited sex‐specific structural alterations across common epilepsies: A worldwide ENIGMA study

open access: yesEpilepsia, EarlyView.
Abstract Objective Epilepsy is characterized by widespread cortical and subcortical structural alterations beyond the epileptic zone. Importantly, the clinical manifestation of epilepsy, including seizure types, psychiatric comorbidities, and treatment responses, has been shown to differ between sexes. However, sex differences in structural alterations
Huantao Wen   +68 more
wiley   +1 more source

Prognosis of acute symptomatic seizures and impact of prolonged treatment with anti‐seizure medication

open access: yesEpilepsia, EarlyView.
Abstract Objectives Acute symptomatic epileptic seizures (ASySs) occur in temporal proximity to acute brain insults. Given their low risk of subsequent unprovoked seizures, current guidelines recommend either no treatment with anti‐seizure medication (ASM) or early discontinuation, yet ASM treatment is often continued beyond hospital discharge.
Hannah Traben   +23 more
wiley   +1 more source

Exploring medical food supplementation as an adjunct strategy for microbiota restoration and seizure reduction in CDKL5 deficiency disorder

open access: yesEpilepsia Open, EarlyView.
Abstract Objectives CDKL5 deficiency disorder (CDD) is a developmental and epileptic encephalopathy characterized by early‐onset, treatment‐resistant seizures and severe neurodevelopmental impairment. Increasing evidence suggests that alterations in the gut–brain axis may contribute to disease pathophysiology, raising interest in microbiota‐targeted ...
Elisa Borghi   +7 more
wiley   +1 more source

Identifying Affective Patterns in Patients With Eating Disorders: A Latent Profile Analysis

open access: yesEuropean Eating Disorders Review, EarlyView.
ABSTRACT Background Emotional difficulties are common among individuals with Eating Disorders (EDs). Following Panksepp's theoretical model, which conceptualises primary emotional systems as the evolutionary foundation of personality, this study aimed to identify distinct profiles of primary emotional systems within a clinical eating disorder (ED ...
Rachele Fasolato   +15 more
wiley   +1 more source

Multi‐Cohort Analysis Reveals Genetic Predispositions to Clonal Hematopoiesis as Mutation‐Specific Risk Factors for Stroke

open access: yesAdvanced Genetics, Volume 6, Issue 1, March 2025.
This study comprehensively evaluated the differential effect of clonal hematopoiesis (CH) mutations on the risk of various stroke subtypes and functional recovery. It shows that TET2 is associated with small vessel stroke possibly via a pro‐inflammatory pathway. Abstract Recent observational studies have found an association between Clonal Hematopoesis
Shuyang Lin, Yang E. Li, Yan Wang
wiley   +1 more source

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