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Challenges arise in researching health effects associated with chemical mixtures. Several methods have recently been proposed for estimating the association between health outcomes and exposure to chemical mixtures, but a formal simulation study ...
Lauren Hoskovec +4 more
doaj +2 more sources
Few studies have considered nutrients as a mixture and their impact on Mild Cognitive Impairment (MCI). The generalized linear regression (GLM), weighted quantile sum (WQS) regression, and Bayesian kernel machine regression (BKMR) models are fitted to ...
Xian Gao +8 more
doaj +2 more sources
Variational Bayesian multinomial probit regression with Gaussian process priors [PDF]
It is well known in the statistics literature that augmenting binary and polychotomous response models with Gaussian latent variables enables exact Bayesian analysis via Gibbs sampling from the parameter posterior.
Rogers, S., Girolami, M.
core +8 more sources
Dietary Selenium and β-Carotene Contribute to the Inverse Association Between Antioxidant Mixtures and Stroke: Evidence From NHANES Using Mixture Models and Machine Learning. [PDF]
In this NHANES study of 37,746 participants, we examined the joint association of six dietary antioxidant‐related nutrients (vitamins A, C, and E, β‐carotene, selenium, and zinc) with stroke, applying 1:1 propensity score matching (matched sub‐cohort, n = 2750), mixture models (WQS, qgcomp, and BKMR), and machine learning with SHAP interpretation ...
Zhong A +6 more
europepmc +2 more sources
Associations between blood essential metal mixture and serum uric acid: a cross-sectional study
IntroductionAlthough several studies have explored the associations between single essential metals and serum uric acid (SUA), the study about the essential metal mixture and the interactions of metals for hyperuricemia remains unclear.MethodsWe ...
Dongmei Wang +16 more
doaj +1 more source
Sparse kernel density construction using orthogonal forward regression with leave-one-out test score and local regularization [PDF]
The paper presents an efficient construction algorithm for obtaining sparse kernel density estimates based on a regression approach that directly optimizes model generalization capability.
Hong, X., Harris, C.J., Chen, S.
core +2 more sources
An orthogonal forward regression technique for sparse kernel density estimation [PDF]
Using the classical Parzen window (PW) estimate as the desired response, the kernel density estimation is formulated as a regression problem and the orthogonal forward regression technique is adopted to construct sparse kernel density (SKD) estimates ...
Chen, Sheng, Hong, X., Harris, Chris J.
core +2 more sources
Background: The infant microbiome contributes to health status across the lifespan, but environmental factors affecting microbial communities are poorly understood, particularly when toxic and essential elements interact.
Hannah E. Laue +5 more
doaj +1 more source
Hierarchic Bayesian models for kernel learning [PDF]
The integration of diverse forms of informative data by learning an optimal combination of base kernels in classification or regression problems can provide enhanced performance when compared to that obtained from any single data source.
Rogers, S. +3 more
core +1 more source
The association between urinary phthalate metabolites and serum thyroid function in US adolescents
The aim was to investigate the association between mixed exposure to phthalates and serum thyroid function among US adolescents. The study used 2007–2008 survey data from the National Health and Nutrition Examination Survey (NHANES).
Shi-ting Xiang +5 more
doaj +1 more source

