Results 21 to 30 of about 5,107,449 (167)

Association between exposure to a mixture of phenols, pesticides, and phthalates and obesity: Comparison of three statistical models

Environment International, 2019
Background: The evaluation of the chemical impact on human health is usually constrained to the analysis of the health effects of exposure to a single chemical or a group of similar chemicals at one time.
Yuqing Zhang, Tianyu Dong, Weiyue Hu, Xu Wang, Bo Xu, Zhongning Lin, Tim Hofer, Pawel Stefanoff, Ying Chen, Xinru Wang, Yankai Xia   +10 more
doaj   +1 more source

Exposure to volatile organic compounds and polycyclic aromatic hydrocarbons is associated with the risk of non-alcoholic fatty liver disease in Korean adolescents: Korea National Environmental Health Survey (KoNEHS) 2015–2017

Ecotoxicology and Environmental Safety, 2023
Non-alcoholic fatty liver disease (NAFLD) is one of the most frequent liver diseases among adolescents. Several animal studies have suggested that volatile organic compounds (VOCs) and polycyclic aromatic hydrocarbons (PAHs) increase NAFLD risk. However,
Yun-Hee Choi, Ju-Yeon Lee, Kyong Whan Moon   +2 more
doaj   +1 more source

Impact of mixtures of persistent organic pollutants on breast cancer aggressiveness

Environment International, 2022
Introduction: Breast cancer (BC) is frequent with a poor prognosis in case of metastasis. The role of the environment has been poorly evaluated in its progression.
Louise Benoit, Meriem Koual, Céline Tomkiewicz, Anne-Sophie Bats, Jean-Philippe Antignac, Xavier Coumoul, Robert Barouki, German Cano-Sancho   +7 more
doaj   +1 more source

Modeling Exposure Mixtures and Spatiotemporal Dependence in Count Data Using Bayesian Kernel Machine Regression

Stats
We propose a Bayesian kernel machine regression (BKMR) framework for count outcomes with dynamic spatiotemporal dependence. The proposed model, termed Negative Binomial BKMR with spatiotemporal effects (NB-BKMR), integrates (i) a negative binomial ...
Ning Sun, Zoran Bursac, Boubakari Ibrahimou   +2 more
doaj   +1 more source

Prenatal metal mixtures and child blood pressure in the Rhea mother-child cohort in Greece

Environmental Health, 2021
Background Child blood pressure (BP) is predictive of future cardiovascular risk. Prenatal exposure to metals has been associated with higher BP in childhood, but most studies have evaluated elements individually and measured BP at a single time point ...
Caitlin G. Howe, Katerina Margetaki, Marina Vafeiadi, Theano Roumeliotaki, Marianna Karachaliou, Manolis Kogevinas, Rob McConnell, Sandrah P. Eckel, David V. Conti, Maria Kippler, Shohreh F. Farzan, Leda Chatzi   +11 more
doaj   +1 more source

Complex environmental contaminant mixtures and their associations with thyroid hormones using supervised and unsupervised machine learning techniques

Environmental Advances, 2021
Evaluating complex mixtures and their associated health effects poses a challenge in human populations. Herein, we assess the association between 17 organic and metal contaminants in blood with thyroid hormones in a remote Indigenous (First Nations ...
Eric N. Liberda, Aleksandra M. Zuk, David S. Di, Robert J. Moriarity, Ian D. Martin, Leonard J.S. Tsuji   +5 more
doaj   +1 more source

A Stacking Ensemble Machine Learning Model for Predicting Vitamin D Deficiency in Bangladeshi Infants

Vector: The Journal of Engineering, Volume 2027, Issue 1, January/December 2027.
This study uses machine learning to predict vitamin D levels in Bangladeshi infants aged 12–24 months, addressing deficiency despite abundant sunlight. A stacking ensemble model combining Gaussian regressor, extra trees and XGBoost achieved the highest accuracy (R2$R^2$: 0.933, RMSE: 3.312).
Sadia Nasrin Tuly, Shatabdi Majumder, Koushik Roy, Md. Easin, Saha Reno, Golam Moktader Nayeem, Ahosan Habib, Atoshi Chowdhury   +7 more
wiley   +1 more source

Cord blood metal(loid) concentrations and bile acid profiles: Insights from mixture analysis

Ecotoxicology and Environmental Safety
Bile acids (BAs) are essential signaling molecules that regulate metabolic and inflammatory processes. However, epidemiological evidence on the influence of metal(loid) mixtures on BA profiles remains scarce, particularly among newborns.
Chuyi Ou, Dan Luo, Lihong Wu, Bibai Du, Di Liu, Jun Yang, Weixiang Wu   +6 more
doaj   +1 more source

Practical considerations for characterization of the external exposome in Alzheimer's disease and related dementias cohorts

Alzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract External exposome research offers opportunities to evaluate complex relationships between multiple environmental determinants of Alzheimer's disease and related dementias (ADRD). However, selecting specific exposure domains, identifying metrics, and downloading, processing, and managing big data are key challenges in translating the potential ...
Zachary Popp, Allison James, Marco Chivardi, Cameron J Reimer, Charlotte Robbins, Tara Jenson, Jeroen M van Baar, Peter James, Kevin J Lane, Marcia Pescador Jiménez   +9 more
wiley   +1 more source

Pesticide Residues, Gut Microbiota, and Gastrointestinal Outcomes: A Scoping Review of Human Evidence

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 5, September 2026.
ABSTRACT Vegetables anchor healthy‐diet recommendations yet are the principal nonoccupational route by which residues of organophosphate (OP), pyrethroid, neonicotinoid, organochlorine (OC), and glyphosate herbicide enter the diet, with the gut microbiota a plausible mediator linking these residues to functional gastrointestinal (GI) and inflammatory ...
Chengqian Ye, Qingjie Wu, Zhaochu Wang, Cai Zhang   +3 more
wiley   +1 more source