Results 251 to 260 of about 520,634 (314)

Splinting in horizontal root fractures: A Bayesian network meta-analysis. [PDF]

PLoS One
Kowaltschuk TC, Gonçalves FM, de Araujo BMM, da Silva Cruz NT, Schroder AGD, Antoniazzi BB, Carneiro E, Alencar MN, Xavier da Silva-Neto U, Guariza-Filho O, de Araujo CM, Westphalen VPD.   +11 more
europepmc   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

Bayesian network meta-analysis of the impact of exercise therapy on blood glucose in type 2 diabetes patients. [PDF]

Front Endocrinol (Lausanne)
Liu H, Wang W, Sun J.
europepmc   +1 more source

N‐of‐1 trials in clinical research: Methodological foundations, statistical approaches and implementation challenges

British Journal of Clinical Pharmacology, EarlyView.
N‐of‐1 trials offer a unique and rigorous methodology for evaluating individualized treatment responses, particularly within the context of personalized medicine. This article provides a comprehensive explanation of the conceptual and methodological underpinnings of N‐of‐1 trials, with particular emphasis on statistical techniques and considerations ...
Marcos Clint Leal De Carvalho, Matheus de Matos Dourado Simões, Ubiratan Cardinalli Adler, Antonio Brazil Viana Junior, Caren Nádia Soares de Sousa, Lia Lira Olivier Sanders   +5 more
wiley   +1 more source

Public Transportation Use, Sexual Harassment, and Mental Health in Adults from the General Population: A Bayesian Network Analysis. [PDF]

Eur J Investig Health Psychol Educ
Baños-Chaparro J, Valencia-Pecho D, Caycho-Rodríguez T, Sarmiento-Suarez E, Bernabel-Tarazona D, Rivera-Álvarez G, Torales J.   +6 more
europepmc   +1 more source

Population pharmacokinetics and dose–response relationships of mitoxantrone in children with acute myeloid leukaemia

British Journal of Clinical Pharmacology, EarlyView.
Background Information on mitoxantrone pharmacokinetics in children is lacking and reduced dosing regimens applied to infants are supported by limited scientific rationale. The current study characterized mitoxantrone pharmacokinetics in a childhood acute myeloid leukaemia patient population and provides a data‐informed assessment of dosing.
Andrew M. Brandon, Hinke Huisman‐Siebinga, Shelby Barnett, Paul Wetherell, Pamela Kearns, Brenda Gibson, Nicholas Heaney, Owen Smith, André Baruchel, Arnaud Petit, Andrew Moore, Kayode Ogungbenro, Alwin D. R. Huitema, Gareth J. Veal   +13 more
wiley   +1 more source

Approaches for Reducing Expert Burden in Bayesian Network Parameterization. [PDF]

Entropy (Basel)
Blomaard BPM, Nane GF, Hanea AM.
europepmc   +1 more source

Mechanism‐informed machine learning for individualized tacrolimus dose adjustment in the early post‐kidney transplant period

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Tacrolimus dosing in the early post‐kidney transplant period is challenging due to a narrow therapeutic index and substantial interindividual pharmacokinetic (PK) variability. This study aimed to develop and validate mechanism‐informed machine learning (ML) models to support individualized tacrolimus dosing during this critical period ...
Hui Yu, Zihan Qin, Logan S. Smith, Jeong M. Park, Hao‐Jie Zhu   +4 more
wiley   +1 more source

Optimal neoadjuvant regimens for locally advanced gastric and gastroesophageal junction cancer: a systematic review and bayesian network meta-analysis. [PDF]

World J Surg Oncol
Fan WQ, Wu YT, Li H, Xu H, Zhu YY, Cheng YR, Peng YH.   +6 more
europepmc   +1 more source

Efficacy and safety of prostaglandin drugs for elevated intraocular pressure: a Bayesian network meta-analysis. [PDF]

Front Med (Lausanne)
Peng J, Huang W, Duan J.
europepmc   +1 more source