Results 121 to 130 of about 4,909,083 (351)

A General Framework for Constrained Bayesian Optimization using Information-based Search [PDF]

open access: green, 2015
José Miguel Hernández-Lobato   +4 more
openalex   +1 more source

CellPolaris: Transfer Learning for Gene Regulatory Network Construction to Guide Cell State Transitions

open access: yesAdvanced Science, EarlyView.
CellPolaris decodes how transcription factors guide cell fate by building gene regulatory networks from transcriptomic data using transfer learning. It generates tissue‐ and cell‐type‐specific networks, identifies master regulators in cell state transitions, and simulates TF perturbations in developmental processes.
Guihai Feng   +27 more
wiley   +1 more source

A general Bayesian algorithm for the autonomous alignment of beamlines

open access: yesJournal of Synchrotron Radiation
Autonomous methods to align beamlines can decrease the amount of time spent on diagnostics, and also uncover better global optima leading to better beam quality.
Thomas W. Morris   +12 more
doaj   +1 more source

Single‐Field Evolution Rule Governs the Dynamics of Representational Drift in Mouse Hippocampal Dorsal CA1 Region

open access: yesAdvanced Science, EarlyView.
Long‐term hippocampal place‐code dynamics are investigated using calcium imaging across weeks of maze navigation. Analyses reveal a novelty‐irrelevant Single‐Field Evolution Rule (SFER), where active fields promote persistence and inactive fields decline.
Cong Chen   +10 more
wiley   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

open access: yesAdvanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang   +12 more
wiley   +1 more source

Deep learning with Bayesian Hyperparameter Optimization for Precise Electrocardiogram Signals Delineation

open access: yesJurnal RESTI (Rekayasa Sistem dan Teknologi Informasi)
Electrocardiography (ECG) serves as an essential risk-stratification tool to observe further treatment for cardiac abnormalities. The cardiac abnormalities are indicated by the intervals and amplitude locations in the ECG waveform.
Annisa Darmawahyuni   +5 more
doaj   +1 more source

Predictive Modeling through Hyper-Bayesian Optimization [PDF]

open access: green, 2023
Manisha Senadeera   +3 more
openalex   +1 more source

CLinNET: An Interpretable and Uncertainty‐Aware Deep Learning Framework for Multi‐Modal Clinical Genomics

open access: yesAdvanced Science, EarlyView.
Identifying disease‐causing genes in neurocognitive disorders remains challenging due to variants of uncertain significance. CLinNET employs dual‐branch neural networks integrating Reactome pathways and Gene Ontology terms to provide pathway‐level interpretability of genomic alterations.
Ivan Bakhshayeshi   +5 more
wiley   +1 more source

Interpretable machine learning approach for TBM tunnel crown convergence prediction with Bayesian optimization

open access: yesFrontiers in Earth Science
Accurate prediction of crown convergence in Tunnel Boring Machine (TBM) tunnels is critical for ensuring construction safety, optimizing support design, and improving construction efficiency.
Wanrui Hu   +6 more
doaj   +1 more source

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