Results 71 to 80 of about 138,439 (148)
Iterative hybrid model based optimization of rAAV production
Abstract Changes in serotype or genetic payload of recombinant adeno associated virus (rAAVs) gene therapies require adapting the transfection conditions of the upstream HEK293 cultivations. This study adopts an iterative model‐based experiment design approach, where increasing data availability is leveraged to evolve models of different complexity ...
Claudio Müller+7 more
wiley +1 more source
Consumer Adoption of Internet of Things
ABSTRACT The Internet of Things (IoT), a pivotal technology in enhancing user connectivity, faces a paradox: its widespread potential yet limited consumer adoption. This study addresses this dichotomy by synthesizing a large‐scale meta‐analytic structural equation modeling (MASEM) and hierarchical linear meta‐analysis (HiLMA) of 2736 effect sizes from ...
Wagner Junior Ladeira+6 more
wiley +1 more source
ABSTRACT Background Precise risk prediction of chronic diseases is essential for effective preventive care and management. Machine learning (ML) is a promising avenue to enhance chronic disease risk prediction; however, a comprehensive assessment of ML performance across various chronic diseases, populations, and health settings is needed. Methods This
Ebenezer Afrifa‐Yamoah+4 more
wiley +1 more source
Bayesian probability of success for clinical trials using historical data. [PDF]
Ibrahim JG+4 more
europepmc +1 more source
Ensemble‐based soil liquefaction assessment: Leveraging CPT data for enhanced predictions
Abstract This study focuses on predicting soil liquefaction, a critical phenomenon that can significantly impact the stability and safety of structures during seismic events. Accurate liquefaction assessment is vital for geotechnical engineering, as it informs the design and mitigation strategies needed to safeguard infrastructure and reduce the risk ...
Arsham Moayedi Far, Masoud Zare
wiley +1 more source
A novel strategy of rational design of transition metal‐based electrocatalyst by combining machine‐learning‐based catalyst optimization steps with experimental verification steps demonstrates that optimized single‐atom nickel incorporated carbon quantum dots presents outstanding electrocatalytic hydrogen production efficiency due to its higher carrier ...
Unbeom Baeck+13 more
wiley +1 more source
Understanding Bayesian analysis of clinical trials: an overview for clinicians. [PDF]
Taylor C, Puxty K, Quasim T, Shaw M.
europepmc +1 more source
Weighing risks against GHG reduction benefits in emerging green technologies
Abstract Green technologies represent promising strategies for mitigating carbon emissions and combating global warming. However, their implementation in civil and industrial applications is not without risks, as intrinsic uncertainties and latent safety concerns can threaten their effective deployment.
Federica Tamburini+3 more
wiley +1 more source
A comparison of frequentist and Bayesian approaches to the Personalised Randomised Controlled Trial (PRACTical)-design and analysis considerations. [PDF]
Jackson H+7 more
europepmc +1 more source