Results 241 to 250 of about 10,357 (300)

Computationally Efficient Approach to Operational Prior Specification in Phase I Clinical Trials

open access: yesStatistics in Medicine, Volume 45, Issue 13-14, June 2026.
ABSTRACT The increased interest in the combination of drug agents and/or schedules requires more flexible model‐based designs for Phase I clinical trials. The models often involve more design parameters, which have to be specified before starting the trial.
Weishi Chen, Pavel Mozgunov
wiley   +1 more source

Fast Estimation and Valid Statistical Inference for Mixed‐Effect Location‐Scale Models Using Variational Inference

open access: yesStatistics in Medicine, Volume 45, Issue 13-14, June 2026.
ABSTRACT With the development of modern technology, richer and more intensive longitudinal data are available for researchers to study more complex model structures. The Mixed‐Effect Location‐Scale Model (MELS) is useful for modeling the variance components in such data.
Brian Ping‐Huan Wu, Donald Hedeker
wiley   +1 more source

GWAS and genomic prediction of crown rust resistance in the southern US elite oat (Avena sativa L.) germplasm

open access: yesThe Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Crown rust (CR), caused by Puccinia coronata f. sp. avenae, is a major constraint to oat (Avena sativa L.) production in the southern United States. We dissected the genetic architecture of CR resistance and assessed genomic prediction in 234 winter and facultative oat lines adapted to the southern United States.
Janam Prabhat Acharya   +8 more
wiley   +1 more source

Association mapping for hop cone chemistry and morphology identifies natural beneficial allele stacks

open access: yesThe Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Efforts are underway to increase the efficiency and precision of selection hop (Humulus lupulus L.) breeding using genomics. Little is known, however, about the genetic control of important traits like α‐and β‐acids contents, oil content, and cone morphological characteristics, all of which play an important role in determining the utility and
Shaun J. Clare   +2 more
wiley   +1 more source

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