Results 101 to 110 of about 548,736 (273)

Shrinkage Confidence Procedures

open access: yes, 2012
The possibility of improving on the usual multivariate normal confidence was first discussed in Stein (1962). Using the ideas of shrinkage, through Bayesian and empirical Bayesian arguments, domination results, both analytic and numerical, have been ...
Casella, George, Hwang, J. T. Gene
core   +1 more source

Single‐Cell Metabolic Imaging and Digital Scoring of Fat Tissue Remodeling by Label‐Free Metabolic Microscopy

open access: yesAdvanced Science, EarlyView.
Mid‐infrared optoacoustic microscopy (MiROM) acquires lipid‐ and protein‐ associated vibrational contrast in intact fat tissue without dyes, preserving native tissue architecture. Through lateral and axial segmentation, MiROM tracks intrinsic intracellular changes during postnatal remodeling. A quantitative spatial analysis tool (Q‐SAT) maps white‐ and
Myeongseop Kim   +7 more
wiley   +1 more source

A Formalism for Expressing the Probability Density Functions of Interrelated Quantities

open access: yesMeasurement Science Review, 2013
In this paper we address measurement problems involving several quantities that are interrelated by model equations. Available knowledge about some of these quantities is represented by probability density functions (PDFs), which are then propagated ...
Lira I., Grientschnig D.
doaj   +1 more source

Lipid‐Facilitated Opening of the ADAM10 Sheddase Revealed by Enhanced Sampling Simulations

open access: yesAdvanced Science, EarlyView.
Phosphatidylserine acts as a lipid trigger to enhance activation of the sheddase ADAM10. By integrating fluorescence spectroscopy assays with enhanced sampling molecular dynamics simulations, this study shows that phosphatidylserine promotes ADAM10 catalytic activity along with expansion of its extracellular domains, enhancing accessibility to scaffold
Adrien Schahl   +7 more
wiley   +1 more source

Teaching Bayesian Statistics To Intelligence Analysts: Lessons Learned

open access: yesJournal of Strategic Security, 2009
The Community must develop and integrate into regular use new tools that can assist analysts in filtering and correlating the vast quantities of information that threaten to overwhelm the analytic process…—Commission on the Intelligence Capabilities of ...
Hemangni Deshmukh   +2 more
doaj  

Entropy as a marker of physiological transition during pediatric cardiopulmonary exercise testing

open access: yesFrontiers in Physiology
This research analyzed the sample entropy (SampEn) of breath-by-breath cardiopulmonary exercise testing (CPET) data from 170 healthy pediatric participants (85 males) 8 to 18-years-old, using a Bayesian statistics approach. SampEn measures the complexity
Kaleigh O’Hara   +5 more
doaj   +1 more source

Bayesian variable selection for high dimensional generalized linear models: convergence rates of the fitted densities

open access: yes, 2007
Bayesian variable selection has gained much empirical success recently in a variety of applications when the number $K$ of explanatory variables $(x_1,...,x_K)$ is possibly much larger than the sample size $n$.
Jiang, Wenxin
core   +1 more source

Activated Platelet–Released Heat Shock Protein 90α Triggers Autophagy‐Dependent Neutrophil Extracellular Trap Formation and Amplifies Sepsis

open access: yesAdvanced Science, EarlyView.
HSP90α is significantly upregulated in platelets from sepsis patients, with its origin from megakaryocyte‐derived trafficking. Furthermore, activated platelets secrete HSP90α into the extracellular space in both free and exosome‐associated forms. Finally, extracellular HSP90α directly engages TLR4 on neutrophils to induce autophagy, leading to NET ...
Chengbo Wang   +17 more
wiley   +1 more source

Equation of State Independent Determination on the Radius of a 1.4 M⊙ Neutron Star Using Mass–Radius Measurements

open access: yesThe Astrophysical Journal Letters
Traditional methods for determining the radius of a 1.4 M _⊙ neutron star ( R _1.4 ) rely on specific equation-of-state (EOS) models that describe various types of dense nuclear matter.
Chun Huang
doaj   +1 more source

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