Results 111 to 120 of about 164,931 (293)

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

Advanced Science, EarlyView.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen, Dandan Dong, Jinling Liao, Naikai Liao, Mengqi Liu, Qin Zhang, Siting Chen, Qi Liu, Ying Lu, Tianyu Li, Chunlin Zou, Qiong Song, Qiuyan Wang, Jian Liang, Qiji Xie, Chengyang Li, Mengyun Wang, Jiwen Cheng, Zengnan Mo, Gong‐Hong Wei   +19 more
wiley   +1 more source

Iron‐Mediated Release of Aged Dissolved Organic Carbon From Waterlogged Peatland Under Warming

Advanced Science, EarlyView.
This study conducts a five‐year in situ warming experiment in high‐altitude peatlands to examine dissolved organic carbon (DOC) release. The study shows that warming promotes the release of plant‐derived modern DOC in drained peatlands, but amplifies aquatic export of century‐old DOC from waterlogged peatlands via Fe‐mediated DOC mobilization—a ...
Guohua Dai, Zhiying Yang, Zongguang Liu, Wanjia Hu, Lixiao Ma, Enze Kang, Wanqing Luo, Yunpeng Zhao, Chengzhu Liu, Juan Jia, Ting Liu, Chen He, Quan Shi, Jianliang Liu, Yongheng Gao, Huai Chen, Hailong Zhang, Meixun Zhao, Xiaojuan Feng   +18 more
wiley   +1 more source

Correlations between the Neutron Star Mass–Radius Relation and the Equation of State of Dense Matter

The Astrophysical Journal
We develop an analytic method of inverting the Tolman–Oppenheimer–Volkoff relations to high accuracy. In principle, a specified energy density–pressure relation gives a unique mass–radius ( M – R ) relation and vice versa.
Boyang Sun, James M. Lattimer
doaj   +1 more source

Entropy as a marker of physiological transition during pediatric cardiopulmonary exercise testing

Frontiers in Physiology
This research analyzed the sample entropy (SampEn) of breath-by-breath cardiopulmonary exercise testing (CPET) data from 170 healthy pediatric participants (85 males) 8 to 18-years-old, using a Bayesian statistics approach. SampEn measures the complexity
Kaleigh O’Hara, Donald E. Brown, Dan M. Cooper, Annamarie Stehli, Shlomit Radom Aizik, Natalie Kupperman   +5 more
doaj   +1 more source

A Formalism for Expressing the Probability Density Functions of Interrelated Quantities

Measurement Science Review, 2013
In this paper we address measurement problems involving several quantities that are interrelated by model equations. Available knowledge about some of these quantities is represented by probability density functions (PDFs), which are then propagated ...
Lira I., Grientschnig D.
doaj   +1 more source

MFPD: A Multiple Fungal Pathogen Detection Pipeline Across Diverse Habitats

Advanced Science, EarlyView.
The MFPD pipeline integrates a comprehensive ITS reference database of fungal pathogens, optimized parameters, and algorithms tailored for both full‐length and subregion sequences that balance accuracy and computational efficiency; it enables high‐throughput, species‐level identification from amplicon sequencing data, supporting large‐scale ...
Yi Shen, Xinrun Yang, Jiabao Yu, Yaozhong Zhang, Tianjie Yang, Yang Gao, Xiaofang Wang, Alexandre Jousset, Waseem Raza, Fang‐Jie Zhao, Qirong Shen, Gaofei Jiang, Zhong Wei, Yangchun Xu   +13 more
wiley   +1 more source

Bayesian computational methods [PDF]

If, in the mid 1980?s, one had asked the average statistician about the difficulties of using Bayesian Statistics, his/her most likely answer would have been ?Well, there is this problem of selecting a prior distribution and then, even if one agrees on ...
Robert, Christian P.
core  

ML Workflows for Screening Degradation‐Relevant Properties of Forever Chemicals

Advanced Science, EarlyView.
The environmental persistence of per‐ and polyfluoroalkyl substances (PFAS) necessitates efficient remediation strategies. This study presents physics‐informed machine learning workflows that accurately predict critical degradation properties, including bond dissociation energies and polarizability.
Pranoy Ray, Andrew R. Castillo, Manoj Kolel‐Veetil, Surya R. Kalidindi   +3 more
wiley   +1 more source

The Contribution of Young Researchers to Bayesian Statistics [PDF]

, 2014
Plenary lecturers and senior discussants of BAYSM 2013 provide a discussion of recent developments in Bayesian statistics Highlights contributions of young researchers to BAYSM 2013 through comprehensive research papers Includes suggested research topics
E., Lanzarone, Ieva, Francesca
core  

Teaching Bayesian Statistics To Intelligence Analysts: Lessons Learned

Journal of Strategic Security, 2009
The Community must develop and integrate into regular use new tools that can assist analysts in filtering and correlating the vast quantities of information that threaten to overwhelm the analytic process…—Commission on the Intelligence Capabilities of ...
Hemangni Deshmukh, Jennifer Lee, Kristan J. Wheaton   +2 more
doaj