Results 41 to 50 of about 164,931 (293)

Bayesian statistics-based analysis of AC impedance spectra

AIP Advances, 2020
AC impedance spectroscopy is an important method for evaluating ionic, electronic, and dielectric properties of materials. In conventional analysis of AC impedance spectra, the selection of an equivalent circuit model and its initial parameters are ...
Yu Miyazaki, Ryo Nakayama, Nobuaki Yasuo, Yuki Watanabe, Ryota Shimizu, Daniel M. Packwood, Kazunori Nishio, Yasunobu Ando, Masakazu Sekijima, Taro Hitosugi   +9 more
doaj   +1 more source

Integration of Multiple Resolution Data in 3D Chromatin Reconstruction Using ChromStruct

Biology, 2021
The three-dimensional structure of chromatin in the cellular nucleus carries important information that is connected to physiological and pathological correlates and dysfunctional cell behaviour.
Claudia Caudai, Monica Zoppè, Anna Tonazzini, Ivan Merelli, Emanuele Salerno   +4 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Epidemiological models, parameters, and prediction of the COVID-19 outbreak in a southwest Georgia hotspot

Journal of the Georgia Public Health Association, 2022
Background: We investigate epidemiological models, their parameters, and the models’ predictive performance of daily new cases during the first three weeks of the SARS-CoV-2 outbreak in a southwest Georgia hotspot.
Daniel F. Linder, William M. Sewell III, Jack D. Owens, Jim Franklin, Mark Miller, Casey Newton, Priyank Shah   +6 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Studying the factors affecting the prevalence of Platyhelminthes in slaughtered ruminants in Lorestan province, Iran (2012-2022)

Journal of Zoonotic Diseases
Production-limiting diseases, such as helminth infections, are a major concern in temperate regions. They can lead to decreased meat and milk production and quality in livestock.
Azadeh Rashidimehr, Hassan Nayebzadeh, Zahra Amini Farsani, Majid Hataminia   +3 more
doaj   +1 more source

A Bayesian robust Kalman smoothing framework for state-space models with uncertain noise statistics

EURASIP Journal on Advances in Signal Processing, 2018
The classical Kalman smoother recursively estimates states over a finite time window using all observations in the window. In this paper, we assume that the parameters characterizing the second-order statistics of process and observation noise are ...
Roozbeh Dehghannasiri, Xiaoning Qian, Edward R. Dougherty   +2 more
doaj   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Bayesian methods for hierarchical distance sampling models [PDF]

, 2014
Cornelia S. Oedekoven was supported by a studentship jointly funded by the University of St Andrews and EPSRC (EPSRC grant EP/C522702/1), through the National Centre for Statistical Ecology.The few distance sampling studies that use Bayesian methods ...
Oedekoven, Cornelia Sabrina, MacKenzie, Monique Lea, M. L. Mackenzie, Buckland, Stephen Terrence, C. S. Oedekoven, S. T. Buckland, L. W. Burger, Evans, Kristine O., King, Ruth, K. O. Evans, Burger, L. W., R. King   +11 more
core   +1 more source