Results 41 to 50 of about 2,194,170 (284)

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Epidemiological models, parameters, and prediction of the COVID-19 outbreak in a southwest Georgia hotspot

Journal of the Georgia Public Health Association, 2022
Background: We investigate epidemiological models, their parameters, and the models’ predictive performance of daily new cases during the first three weeks of the SARS-CoV-2 outbreak in a southwest Georgia hotspot.
Daniel F. Linder, William M. Sewell III, Jack D. Owens, Jim Franklin, Mark Miller, Casey Newton, Priyank Shah   +6 more
doaj   +1 more source

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi, Giorgio Ricciardiello Mejia, Andre Metzger, Kang Hyun Ryu, Salonee Marwaha, Eva Grzegorczyk, Li Zhou, Eliana Jacobs, Boris Gilyadov, Claudia Kunney, Liqhwa Ncube, Ankit Parekh, Emmanuel Mignot, Fanny M. Elahi, Joseph Winer, Kathleen Poston, Andreas Brink‐Kjaer, Emmanuel H. During   +17 more
wiley   +1 more source

Bayesian curve estimation by model averaging [PDF]

, 2003
A bayesian approach is used to estimate a nonparametric regression model. The main features of the procedure are, first, the functional form of the curve is approximated by a mixture of local polynomials by Bayesian Model Averaging (BMA); second, the ...
Peña, Daniel, Redondas, María Dolores
core   +1 more source

Studying the factors affecting the prevalence of Platyhelminthes in slaughtered ruminants in Lorestan province, Iran (2012-2022)

Journal of Zoonotic Diseases
Production-limiting diseases, such as helminth infections, are a major concern in temperate regions. They can lead to decreased meat and milk production and quality in livestock.
Azadeh Rashidimehr, Hassan Nayebzadeh, Zahra Amini Farsani, Majid Hataminia   +3 more
doaj   +1 more source

A Bayesian robust Kalman smoothing framework for state-space models with uncertain noise statistics

EURASIP Journal on Advances in Signal Processing, 2018
The classical Kalman smoother recursively estimates states over a finite time window using all observations in the window. In this paper, we assume that the parameters characterizing the second-order statistics of process and observation noise are ...
Roozbeh Dehghannasiri, Xiaoning Qian, Edward R. Dougherty   +2 more
doaj   +1 more source

Global Rather Than Vertical‐Selective Saccadic Abnormalities in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To test whether vertical saccades are preferentially affected in Progressive Supranuclear Palsy (PSP). Methods PSP patients (n = 24) were compared to age‐matched controls (n = 94) and two degenerative groups (Alzheimer's disease, n = 20; Lewy body disease, n = 50).
Duy Duan Nguyen, Mark Paine, Soohyun Lee, Amir Fazlollahi, Baibin (Ben) Wang, John D. O'Sullivan, Peter J. Nestor   +6 more
wiley   +1 more source

Approximation of Bayesian predictive p-values with\ud regression ABC [PDF]

, 2018
In the Bayesian framework a standard approach to model criticism is to compare some function of the observed data to a reference predictive distribution.
Mengersen, Kerrie, Evans, Michael, Nott, David J., Drovandi, Christopher C., Drovandi, C.C., Mengersen, K., Nott, D.J., Evans, M.   +7 more
core   +1 more source

Bayesian Statistics Then and Now

Statistical Science, 2010
Discussion of "The Future of Indirect Evidence" by Bradley Efron [arXiv:1012.1161]
openaire   +3 more sources

Biopsychosocial Determinants of Hand Function and Its Trajectories Over Five Years in Patients With Hand Osteoarthritis

Arthritis Care &Research, EarlyView.
Objective This study aimed to investigate hand function trajectories over five years in primary hand osteoarthritis (OA). Additionally, determinants of baseline and longitudinal hand function were assessed. Methods A total of 538 patients with both baseline and five‐year study visits were analyzed.
Annemiek V. E. M. Olde Meule, Coen van der Meulen, Jos Runhaar, Frits R. Rosendaal, Margreet Kloppenburg   +4 more
wiley   +1 more source