Results 51 to 60 of about 164,931 (293)

BAYESIAN LOCAL FALSE DISCOVERY RATE FOR SPARSE COUNT DATA WITH APPLICATION TO THE DISCOVERY OF HOTSPOTS IN PROTEIN DOMAINS [PDF]

, 2022
In cancer research at the molecular level, it is critical to understand which somatic mutations play an important role in the initiation or progression of cancer. Recently, studying cancer somatic variants at the protein domain level is an important area
Kann, Maricel G., Maricel G. Kann, Ilia Rattsev, Gauran, Iris Ivy M., Peterson, Thomas A., Park, DoHwan, Iris Ivy M. Gauran, Rattsev, Ilia, Junyong Park, Park, Junyong, Thomas A. Peterson, DoHwan Park   +11 more
core   +1 more source

The concept of probability, crisis in statistics, and the unbearable lightness of Bayesing

Science & Philosophy, 2023
Education in statistics, the application of statistics in scientific research, and statistics itself as a scientific discipline are in crisis. Within science, the main cause of the crisis is the insufficiently clarified concept of probability.
Boris Čulina
doaj   +1 more source

Efficacy of Inebilizumab in N‐MOmentum Trial Participants With or Without Prior Immunosuppressants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This post hoc analysis examined the impact of prior immunosuppressants on the long‐term efficacy and safety of inebilizumab, a cluster of differentiation 19+ B‐cell–depleting monoclonal antibody, in participants with aquaporin‐4–seropositive neuromyelitis optica spectrum disorder from the N‐MOmentum trial (NTC02200770).
Bruce A. C. Cree, Beatrice Suero, Sarah Walsh, Romain Marignier, John W. Lindsey, Ho Jin Kim, Dewei She, Daniel Cimbora, Dustin Cavida, Friedemann Paul   +9 more
wiley   +1 more source

Introduction to Bayesian statistics [PDF]

, 2019
In this workshop, I will provide an introduction to the Bayesian paradigm for data analysis, focusing on both parameter estimation and hypothesis testing.
Ellis, Andrew
core  

Bayesian nonparametric estimators derived from conditional Gibbs structures [PDF]

, 2008
We consider discrete nonparametric priors which induce Gibbs-type exchangeable random partitions and investigate their posterior behavior in detail.
PRUENSTER, IGOR, Lijoi, Antonio, Walker, Stephen G., PRUENSTER I., Prunster, Igor, WALKER S. G.   +5 more
core   +1 more source

Baby Boomers in Germany: a secondary data analysis of demographics, regional disparities, healthcare utilization, and mortality

BMC Public Health
Background The demographic shift driven by the aging Baby Boomer cohort represents a substantial burden for our healthcare system. The aim of this study is to analyze the basic demographic characteristics, regional disparities, healthcare utilization ...
Andreas Kuehnl, Volker J. Schmid, Michaela Olm, Wolfgang Weber   +3 more
doaj   +1 more source

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi, Giorgio Ricciardiello Mejia, Andre Metzger, Kang Hyun Ryu, Salonee Marwaha, Eva Grzegorczyk, Li Zhou, Eliana Jacobs, Boris Gilyadov, Claudia Kunney, Liqhwa Ncube, Ankit Parekh, Emmanuel Mignot, Fanny M. Elahi, Joseph Winer, Kathleen Poston, Andreas Brink‐Kjaer, Emmanuel H. During   +17 more
wiley   +1 more source

Reliability and Feasibility of Linear Mixed Models in Fully Crossed Experimental Designs

Advances in Methods and Practices in Psychological Science
The use of linear mixed models (LMMs) is increasing in psychology and neuroscience research In this article, we focus on the implementation of LMMs in fully crossed experimental designs.
Michele Scandola, Emmanuele Tidoni
doaj   +1 more source

Global Rather Than Vertical‐Selective Saccadic Abnormalities in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To test whether vertical saccades are preferentially affected in Progressive Supranuclear Palsy (PSP). Methods PSP patients (n = 24) were compared to age‐matched controls (n = 94) and two degenerative groups (Alzheimer's disease, n = 20; Lewy body disease, n = 50).
Duy Duan Nguyen, Mark Paine, Soohyun Lee, Amir Fazlollahi, Baibin (Ben) Wang, John D. O'Sullivan, Peter J. Nestor   +6 more
wiley   +1 more source

Bayesian statistics in educational research: a look at the current state of affairs [PDF]

, 2018
The ability of a scientific discipline to build cumulative knowledge depends on its predominant method of data analysis. A steady accumulation of knowledge requires approaches which allow researchers to consider results from comparable prior research ...
König, Christoph, Methodology and statistics for the behavioural and social sciences, van de Schoot, Rens, Leerstoel Hoijtink   +3 more
core   +1 more source