Results 51 to 60 of about 548,736 (273)

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

Frequentist optimality of Bayesian wavelet shrinkage rules for Gaussian and non-Gaussian noise [PDF]

open access: yes, 2006
The present paper investigates theoretical performance of various Bayesian wavelet shrinkage rules in a nonparametric regression model with i.i.d. errors which are not necessarily normally distributed.
Pensky, Marianna
core   +4 more sources

Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz   +8 more
wiley   +1 more source

Quantitative Framework for Astrobiology Strategies and in situ Biogenic Assessments

open access: yesFrontiers in Astronomy and Space Sciences, 2022
In July 2020, NASA’s Perseverance (Mars 2020) mission was launched. The rover sent to the surface of Mars will not only perform in situ analyses, but will also collect rock and regolith samples that will be returned to Earth by future missions for ...
Julie Hartz, Simon C. George
doaj   +1 more source

Bayesian Reconstruction of Approximately Periodic Potentials at Finite Temperature [PDF]

open access: yes, 2000
The paper discusses the reconstruction of potentials for quantum systems at finite temperatures from observational data. A nonparametric approach is developed, based on the framework of Bayesian statistics, to solve such inverse problems.
Lemm, J. C., Uhlig, J., Weiguny, A.
core   +2 more sources

Effectiveness and Safety of Baricitinib for Juvenile Idiopathic Arthritis–Associated Uveitis or Chronic Anterior Antinuclear Antibody–Positive Uveitis

open access: yesArthritis Care &Research, EarlyView.
Objective To evaluate the efficacy and safety of baricitinib in pediatric patients with active juvenile idiopathic arthritis–associated uveitis (JIA‐U) or chronic anterior antinuclear antibody–positive uveitis, who had an inadequate response to methotrexate (MTX) or biologic disease‐modifying antirheumatic drugs (bDMARDs).
Athimalaipet V. Ramanan   +7 more
wiley   +1 more source

Recent Applications of Bayesian Methods to the Solar Corona

open access: yesFrontiers in Astronomy and Space Sciences, 2022
Solar coronal seismology is based on the remote diagnostics of physical conditions in the corona of the Sun by comparison between model predictions and observations of magnetohydrodynamic wave activity.
Iñigo Arregui, Iñigo Arregui
doaj   +1 more source

Model-robust regression and a Bayesian ``sandwich'' estimator [PDF]

open access: yes, 2010
We present a new Bayesian approach to model-robust linear regression that leads to uncertainty estimates with the same robustness properties as the Huber--White sandwich estimator.
Lumley, Thomas   +2 more
core   +3 more sources

Addressing Economic Insecurities Can Improve Patient‐Reported Outcomes in Lupus

open access: yesArthritis Care &Research, Accepted Article.
Background Economic insecurities, such as food, housing, transportation, and financial challenges, are modifiable risk factors and influence patient‐reported outcomes (PROs) in systemic lupus erythematosus (SLE). We examined: 1) associations between economic insecurities and PROs; 2) the impact of screening and addressing economic insecurities during ...
Jay Patel   +8 more
wiley   +1 more source

Agricultural Expansion in Mato Grosso from 1986–2000: A Bayesian Time Series Approach to Tracking Past Land Cover Change

open access: yesRemote Sensing, 2020
Landsat 5 has produced imagery for decades that can now be viewed and manipulated in Google Earth Engine, but a general, automated way of producing a coherent time series from these images—particularly over cloudy areas in the distant past—is
Jacky Lee   +2 more
doaj   +1 more source

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