Abstract We establish the consistency and the asymptotic distribution of the least squares estimators of the coefficients of a subset vector autoregressive process with exogenous variables (VARX). Using a martingale central limit theorem, we derive the asymptotic normal distribution of the estimators. Diagnostic checking is discussed using kernel‐based
Pierre Duchesne +2 more
wiley +1 more source
A parametric survival model with bayesian structural equation based on multi-omics integration. [PDF]
Chu J +8 more
europepmc +1 more source
Hidden Markov graphical models with state‐dependent generalized hyperbolic distributions
Abstract In this article, we develop a novel hidden Markov graphical model to investigate time‐varying interconnectedness between different financial markets. To identify conditional correlation structures under varying market conditions and accommodate shape features embedded in financial time series, we rely upon the generalized hyperbolic family of ...
Beatrice Foroni +2 more
wiley +1 more source
Moderated mediation with composites: The composite moderated structural equations approach. [PDF]
Schamberger T, Schuberth F, Henseler J.
europepmc +1 more source
A partial envelope approach for modelling multivariate spatial‐temporal data
Abstract In the new era of big data, modelling multivariate spatial‐temporal data is a challenging task due to both the high dimensionality of the features and complex associations among the responses across different locations and time points.
Reisa Widjaja +3 more
wiley +1 more source
Genomic Structural Equation Modeling Provides an Initial View of the Genetic Architecture Related to Type 1 Gaucher Disease. [PDF]
Ren S, Du M, Liu J, Li B, Liu J, Lang X.
europepmc +1 more source
Repurposing Drugs for Malaria through a Human Dose Prediction: A Case Study with Berzosertib
Repurposing drugs whose clinical safety has been established offers a valuable approach to reduce the cost and time associated with the development of new drugs for malaria. Here, we investigate the potential to repurpose the anticancer kinase inhibitor berzosertib for the treatment of malaria, by assessing whether a predicted efficacious human dose ...
Devasha Redhi +5 more
wiley +1 more source
Maximum Likelihood and Bayesian Estimation in Cross-Domain Latent Growth Curve Modeling: The Impact of Reliability, Sample Size, and Missing Data. [PDF]
Rafiee P, Pauley E, Yang M.
europepmc +1 more source
The Visual Predictive Check and Real‐World Data
The visual predictive check (VPC) is a standard tool for assessing pharmacometric model suitability, producing visualizations that compare observed data with simulated data such that both model structure and model variability terms can be assessed. However, real‐world data commonly reflect clinical decision‐making that adapts therapy in response to ...
Jasmine H. Hughes +2 more
wiley +1 more source
Redefining Parameter Estimation and Covariate Selection via Variational Autoencoders: One Run Is All You Need. [PDF]
Rohleff J +7 more
europepmc +1 more source

