Results 51 to 60 of about 2,298,955 (274)

Talking About My Generation: the Date of the West Kennet Long Barrow [PDF]

open access: yes, 2007
Thirty-one radiocarbon results are now available from the West Kennet long barrow, and are presented within an interpretive Bayesian statistical framework.
Bayliss, A   +2 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Pregnancy-associated breast cancer: course, diagnosis and treatment

open access: yesАкушерство, гинекология и репродукция
Pregnancy-associated breast cancer (ВС) is a rare pathology in the practice of an obstetrician-gynecologist and oncologist, which diagnostics is coupled to certain difficulties.
I. A. Salov   +3 more
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Constraining the relative velocity effect using the Baryon Oscillation Spectroscopic Survey [PDF]

open access: yes, 2017
We analyse the power spectrum of the Baryon Oscillation Spectroscopic Survey (BOSS), Data Release 12 (DR12) to constrain the relative velocity effect, which represents a potential systematic for measurements of the Baryon Acoustic Oscillation (BAO) scale.
Beutler, Florian   +2 more
core   +2 more sources

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

The Role of Contrast-Enhanced Imaging Methods in Breast Cancer Early Diagnostics and Treatment Planning

open access: yesВестник рентгенологии и радиологии
Оn March 27, 2023, а multidisciplinary Advisory Board meeting was held in Moscow with the participation of Е.V. Artamonova, Е.А. Busko, V.V. Didenko, А.D. Zikiryakhodzhaev, М.S. Karpova, G.Е. Kvetenadze, P.V. Krivorot’ko, М.L. Mazo, А.V.
I. Е. Tyurin   +13 more
doaj   +1 more source

Carving Out an Epistemological Space: EAL Teaching and Learning as a Field of Inquiry

open access: yesBC TEAL Journal, 2022
The BC TEAL Journal continues to strengthen the field of English as an additional language (EAL) teaching and learning as a space for authors, reviewers, editors, and readers to come together in ways that underscore the knowledge creation, theory ...
Scott Roy Douglas
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

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