Results 301 to 310 of about 150,149 (335)

Sesamin alleviates androgenetic alopecia by targeting the AR MAPK Wnt axis. [PDF]

Sci Rep
Li Y, Chen J, Xi R, Tang Q, Gao T, Qian Y, Huang Z, Ding B, Cao Y.   +8 more
europepmc   +1 more source

A Cell‐Intrinsic Role for RANK in Regulatory T Cells of the Human Thymus

European Journal of Immunology, Volume 56, Issue 2, February 2026.
We identified RANK (TNFRSF11a) expression in human thymic FOXP3+ Tregs, revealing a previously unknown role for the RANK‐RANKL axis in human tTreg development. We show that IL‐2 and IL‐15 can drive RANK expression in CD4+ tTregs, which in turn may modulate their maturation and proliferation within the thymic environment. Created in BioRender. Biorender,
Zoe‐Isabella Junginger, Ramona Adameck, Alexandre A. S. F. Raposo, Pedro Rosmaninho, Ana E. Sousa, Afonso R. M. Almeida   +5 more
wiley   +1 more source

Extracellular vesicle-associated lncRNA LYPLAL1-DT mediates endothelial-cancer cell communication, promoting small cell lung cancer progression. [PDF]

Extracell Vesicles Circ Nucl Acids
Zhang X, Hu C, Li Z, Lu J, Huo X, Cao L, Guo M, Li C, Liu X, Chen Z, Lv J, Du X.   +11 more
europepmc   +1 more source

Salvia coccinea and Apigenin: A Natural Treasure of Lamiaceae in Pharmacological Innovation

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Salvia coccinea is rich in bioactive phytochemicals, notably the flavonoid apigenin, offering strong antioxidant, anti‐inflammatory, and antimicrobial effects. By modulating inflammatory and oxidative pathways, it shows potential for managing chronic diseases.
Muhammad Usman Khalid, Muhammad Tauseef Sultan, Muhammad Maaz, Shehnshah Zafar, Anum Shoukat, Nudrat Khursheed, Matteo Bordiga, Amna Junaid   +7 more
wiley   +1 more source

EIF4A3‐Induced Circular RNA circSnd1 Promotes Muscle Atrophy and Muscle Ageing by Stabilizing EEF1A1

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Muscle atrophy is a common complication of ageing, and many chronic conditions, lacks defined therapeutic interventions. It is still mostly unknown how circular RNAs contribute to muscle atrophy. Methods circRNA sequencing and quantitative real‐time PCR were performed to detect the changed circRNAs in muscle atrophy models and aged ...
Jin Li, Bing Jin, Yuwei Yan, Yuying Chen, Xiaohang Yin, Xinyi Ren, Qian Li, Jingying Chen, Siqi Wang, Tingting Yang, Yanan Zhang, Qiumeng Nie, Dongchao Lu, Ming Wu, Yan Yu, Lei Chen, Tarun Keswani, Guoping Li, Dragos Cretoiu, T. Scott Bowen, Junjie Xiao, Yongjun Zheng   +21 more
wiley   +1 more source

Largely Distinct Post‐Translational Modifications Differentiate Skeletal Muscle Wasting Caused by Cancer, Dexamethasone and Aging

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Skeletal muscle wasting and weakness are prominent disease features. Originally considered to arise from common transcriptional changes, recent analyses demonstrated that different stimuli induce muscle wasting via largely distinct mRNA and protein changes.
Anna Stephan, Flavia A. Graca, Suresh Poudel, Yingxue Fu, Yong‐Dong Wang, Myriam Labelle, Fabio Demontis   +6 more
wiley   +1 more source

Cytogenomic Abnormalities in Children With Acute Lymphoblastic Leukemia From Western Mexico: A Single‐Center Fluorescence In Situ Hybridization‐Based Study

eJHaem, Volume 7, Issue 1, February 2026.
ABSTRACT Introduction In Mexico, the 5‐year overall survival (OS) rate for pediatric acute lymphoblastic leukemia (ALL) ranges from 45% to 85%, markedly lower than the ∼90% reported in high‐income countries, where cytogenomic testing is essential for accurate risk stratification and therapeutic decision‐making.
Rosa María González Arreola, María Teresa Magaña Torres, Ma. Guadalupe Domínguez Quezada, Janet Margarita Soto Padilla, José Luis Toro Castro, Beatriz Kazuko De la Herrán Arita, Alicia Gutiérrez Méndez, Hugo Antonio Romo Rubio, Juan Ramón González García   +8 more
wiley   +1 more source

A Novel Human Cellular System for Studying Normal Aging and for Anti‐Aging Discovery

Aging Cell, Volume 25, Issue 2, February 2026.
This study introduces a human cellular aging model using placental trophoblasts (hTSC‐STBs) that mimics key aging features like senescence and genomic instability. It aligns with human tissue aging and responds to anti‐aging treatments, offering a scalable platform to screen potential therapies and bridge lab findings to clinical applications ...
Zhen Feng, Cheuk Shuen Li, Haifeng Fu, Wenxin Jiang, Weiyu Zhang, Yingzhang Huang, Yunying Huang, Timothy Theodore Ka Ki Tam, Yang Li, Fang Liu, Liming Lu, Yin Lau Lee, William Shu Biu Yeung, Gordon Dougan, Pentao Liu   +14 more
wiley   +1 more source

Hedyotis diffusae herba -Scutellaria Barbata herba drug pair suppresses prostate cancer by inducing apoptosis. [PDF]

Sci Rep
Qiu J, Wu L, Hong Z, Shi Y, Wei Y, Wang Q, Chen Z, Chen W, Zhang Q, You XJ, Zhou WB, Zhou W.   +11 more
europepmc   +1 more source

Bibliometric analysis and core target identification of network pharmacology on neuroinflammation in central nervous system disorders: Trends, collaborations, and future directions. [PDF]

Neuroprotection
Zhang Y, Hou S, Li J, Wang W, Jia S, Wang X, Xia Y, Wang Y.   +7 more
europepmc   +1 more source