Results 161 to 170 of about 290,825 (294)

Site-specific profiling of structure and function of Igµ B cell receptor glycans. [PDF]

Nat Commun
Holborough-Kerkvliet MD, Hafkenscheid L, Kroos S, Biersteker R, van de Wetering R, Singh O, Fadda E, Tjokrodirijo RTN, van Veelen PA, Wuhrer M, Falck D, Toes REM.   +11 more
europepmc   +1 more source

Improved survival with fludarabine‐based therapies in mixed phenotype acute leukaemia: A population‐based study using the WHO 2022 classification

British Journal of Haematology, EarlyView.
Summary Mixed phenotype acute leukaemia (MPAL) is a rare subtype of acute leukaemia possessing significant therapeutic challenges, as no standardized, evidence‐based treatment regimen has been defined. In this nationwide study, we aimed to assess the effect of an acute lymphoid leukaemia (ALL)‐like regimen; an acute myeloid leukaemia (AML)‐like regimen;
Lisa‐Maj Christensen, Mikkel Runason Simonsen, Jonas Faartoft Jensen, Daniel Tuyet Kristensen, Karen Dybkær, Kirsten Grønbæk, Tarec Christoffer El‐Galaly, Marianne Schmidt Ettrup, Hans Beier Ommen, Anne Louise Tølbøll Sørensen, Dennis Lund Hansen, Marianne Tang Severinsen   +11 more
wiley   +1 more source

Targetable Vulnerabilities in MYC-Driven B Cell Lymphomas Resistant to BCR Extinction. [PDF]

Hematol Oncol
Brambillasca S, Parr NC, Palmeri A, Andronache A, Arima H, Faga' G, Leuzzi B, Perucho L, Robusto M, Pasi M, Mainoldi F, Fancelli D, Varasi M, Varano G, Mercurio C, Casola S.   +15 more
europepmc   +1 more source

3D‐printed model for resection of positive surgical margins in robot‐assisted prostatectomy

BJU International, Volume 135, Issue 4, Page 657-667, April 2025.
Objectives To improve precision of secondary resection (SR) after positive surgical margin (PSM) detection by frozen section (FS) during nerve‐sparing (NS) robot‐assisted radical prostatectomy (RARP) by employing a personalised three‐dimensional (3D)‐printed prostate model derived from pelvic magnetic resonance imaging (MRI).
Christian Engesser, Philipp Brantner, Brigitta Gahl, Matthias Walter, Julian Gehweiler, Helge Seifert, Svetozar Subotic, Cyrill Rentsch, Christian Wetterauer, Lukas Bubendorf, Tatjana Vlajnic, Abolfazl Hosseini, Jan Ebbing   +12 more
wiley   +1 more source

Multimodal gene and targeted drug therapy for chronic myelogenous leukemia using BIM/MCL-1 chimeric nanoparticle: computational target analysis and therapeutic validation. [PDF]

Nano Converg
Lugin ML, Lei W, Lee RT, Chung JY, Katritsis NM, Hwang W, Fleischman AG, Han N, Kwon YJ.   +8 more
europepmc   +1 more source

The cost‐effectiveness of intraoperative margin assessment strategies during radical prostatectomy

BJU International, EarlyView.
Objective To determine whether current intraoperative margin assessment (IOMA) techniques (such as Neurovascular Structure Adjacent Frozen‐section Examination [NeuroSAFE] or confocal laser microscopy [CLM]) used during radical prostatectomy (RP) to enhance nerve‐sparing surgery (NSS) while reducing positive surgical margins (PSMs) justify their extra ...
Joost van Drumpt, Tim Govers, Ricardo Almeida‐Magana, Diederik Baas, Aiman Haider, Michiel Sedelaar, Greg Shaw, Diederik Somford   +7 more
wiley   +1 more source

B cell receptor signaling in autoimmune rheumatic diseases: regulatory mechanisms and therapeutic targeting. [PDF]

Front Immunol
Zhu Y, Gao L, Han Y, Liu F, Xie X, Dai X, Wang Y, Guo Y, Luo C, Chen Y, Huang P, Du Z.   +11 more
europepmc   +1 more source

Impact of positive surgical margins on biochemical recurrence and metastases after radical prostatectomy

BJU International, EarlyView.
Objectives To evaluate the impact of the presence, extent and location of positive surgical margins (PSMs) on the risk of biochemical recurrence (BCR) and metastases in a nationwide cohort of patients who underwent radical prostatectomy (RP) and had 5 years of follow‐up.
Joost van Drumpt, Diederik Baas, Katja Aben, Arno van Leenders, Lambertus Kiemeney, Michiel Sedelaar, Peter Mulders, Jean‐Paul van Basten, Inge van Oort, Berdine Heesterman, Diederik Somford   +10 more
wiley   +1 more source

Development and validation of an online predictive model for biochemical recurrence after radical prostatectomy in elderly patients. [PDF]

Front Oncol
Liu J, Tan H, Lv Y, Xiao B, Wu X, Wu F, Xiao M.   +6 more
europepmc   +1 more source

Guideline of guidelines: pelvic lymph node dissection at time of radical prostatectomy

BJU International, EarlyView.
Objective To provide a comprehensive review, analysis and critique of guidelines from various oncological and urological organisations regarding the use pelvic lymph node dissection (PLND) in men undergoing radical prostatectomy (RP) for primary treatment of prostate cancer (PCa).
Jonathon Carll, Jonathan Walbaum, Carlos Delgado, Elena Berg, Declan G. Murphy, Marlon Perera, Ahmed Adam, John Yaxley, Nathan Lawrentschuk   +8 more
wiley   +1 more source