Results 191 to 200 of about 288,388 (279)

Ph‐Negative Acute Lymphoblastic Leukemia in the Older Adults: Biology, Therapeutic Strategies and Unmet Needs

European Journal of Haematology, EarlyView.
ABSTRACT Acute lymphoblastic leukaemia (ALL) in older adults represents a growing clinical challenge, driven by an ageing population, adverse disease biology, and reduced tolerance to intensive chemotherapy. Although pediatric‐inspired regimens have improved outcomes in younger adults with Philadelphia chromosome (Ph)‐negative ALL, survival in older ...
Antonella Bruzzese, Ernesto Vigna, Enrica Antonia Martino, Santino Caserta, Francesco Mendicino, Maria Eugenia Alvaro, Caterina Labanca, Eugenio Lucia, Virginia Olivito, Marco Fiorillo, Nicola Amodio, Fortunato Morabito, Massimo Gentile   +12 more
wiley   +1 more source

Identification of a <i>Musashi2</i> translocation as a novel oncogene in myeloid leukemia. [PDF]

Elife
Spinler K, Hamilton M, Bajaj J, Shima Y, Diaz E, Kritzik M, Reya T.   +6 more
europepmc   +1 more source

Current perspectives on KMT2A fusion proteins and menin inhibition in paediatric acute myeloid leukaemia

The FEBS Journal, EarlyView.
Genetic rearrangements resulting in the expression of KMT2A fusion alleles can lead to dramatic transcriptional disturbances that contribute to the onset of acute leukaemias. Fortunately, menin inhibition has emerged as a promising new class of targeted therapy.
Lydia Elaine Roets, Graeme Greenfield, Katrina Mairead Lappin   +2 more
wiley   +1 more source

Development and Validation of a Standardized Palpebral Conjunctival Redness Scale. [PDF]

Cureus
Lim JW, Wong CW, Seto NA, Le HL, Yee RW.
europepmc   +1 more source

A Common Reference Material for Mass‐Dependent Sn Isotope Compositions: An Inter‐Laboratory Calibration Approach

Geostandards and Geoanalytical Research, EarlyView.
Key Points We recommend using the notation δ122/118SnNIST SRM 3161a for mass‐dependent Sn isotope data. We derived conversion factors relative to NIST SRM 3161a for Puri Sn CEZA (0.132 ± 0.011‰), Sn Lyon (0.229 ± 0.016‰), Sn IPGP (0.162 ± 0.018‰). Tin isotope compositions are presented for SPEX CertiPrep Sn and nine USGS reference materials.
Aurélia C.E. Meister, Manuela A. Fehr, Quentin Amet, Gerhard Brügmann, Caroline Fitoussi, Matthias Friebel, Weiqiang Li, Frederic Moynier, Jia‐Xin She, Xueying Wang, Maria Schönbächler   +10 more
wiley   +1 more source

Prognostic features of biochemical recurrence of prostate cancer following radical prostatectomy based on diffusion kurtosis imaging. [PDF]

Cancer Imaging
Lin LP, Cheng XW, Chen J, Li SY, Bian J, He JK, Liu DM, Liu QY, Zhou KP.   +8 more
europepmc   +1 more source

New Potential Haematite and Magnetite Reference Materials for Iron Isotope Measurements by Solution Nebulisation MC‐ICP‐MS and by In Situ ns‐LA‐MC‐ICP‐MS

Geostandards and Geoanalytical Research, EarlyView.
Key Points Two haematite and magnetite materials were developed as potential Fe isotope reference materials. Solution and in situ LA‐MC‐ICP‐MS analyses yielded consistent δ56Fe values. Both materials are isotopically homogeneous and suitable for in situ Fe isotope calibration.
Jialu Yu, Marcus Oelze, Mathias Schannor, Simon Nordstad, Jochen Vogl   +4 more
wiley   +1 more source

Metastasis-Free Survival in Patients with Biochemical Recurrence After Robot-Assisted Radical Prostatectomy: A Multicenter, Retrospective Cohort Study in Japan (MSUG94 Group). [PDF]

Curr Oncol
Nezasa M, Tomioka M, Tatenuma T, Sasaki T, Ikehata Y, Nakayama A, Toide M, Yoneda T, Sakaguchi K, Makiyama K, Inoue T, Kitamura H, Saito K, Koga F, Urakami S, Koie T.   +15 more
europepmc   +1 more source

Significance of Myelodysplasia‐Related Mutations and the Genetic Landscape of Acute Leukemias of Ambiguous Lineage

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT The recent fifth edition WHO classification and ICC classification systems have moved further toward genetically defined classifications of acute leukemias. Both now recognize myelodysplasia‐related (MR) mutations as defining of MDS‐related AML (AML‐MR).
Timothy J. Kirtek, Olga K. Weinberg
wiley   +1 more source

Robotic assisted radical prostatectomy improves biochemical recurrence-free survival: The PROCA-life study. [PDF]

J Robot Surg
Knutsen T, Aarsaether E, Wilsgaard T, Støyten M, Stikbakke E, Richardsen E, Larsen M, Thune I, Haugnes HS.   +8 more
europepmc   +1 more source