Results 1 to 10 of about 112,698 (266)

Management of chronic myeloid leukemia in 2025. [PDF]

Cancer
AbstractChronic myeloid leukemia (CML) has an annual incidence of approximately two cases per 100,000. The reduction in annual mortality from 10%–20% to 1% with BCR::ABL1 tyrosine kinase inhibitors (TKIs) has resulted in an increased prevalence in the United States of an estimated 150,000 cases in 2025.
Kantarjian H, Breccia M, Haddad FG, Hehlmann R, Issa GC, Malhotra H, Nicolini FE, Sasaki K, Stenke L, Jabbour E.   +9 more
europepmc   +5 more sources

Up-regulation of SNHG5 Expression Level in Patients with Chronic Myeloid Leukemia Compared with Normal Individuals [PDF]

مجله دانشکده پزشکی اصفهان, 2022
Background: Chronic myeloid leukemia is a type of myeloproliferative malignancy that is associated with translocation between chromosomes 9 and 22 and accounts for approximately 15% of all leukemia.
Zahra Shahpouri-Arani, Mohamad Reza Hajari, Javad Mohammadi-Asl, Najmaldin Saki   +3 more
doaj   +1 more source

Integrating genetic and epigenetic factors in chronic myeloid leukemia risk assessment: toward gene expression-based biomarkers

Haematologica, 2021
Cancer treatment is constantly evolving from a one-size-fits-all towards bespoke approaches for each patient. In certain solid cancers, including breast and lung, tumor genome profiling has been incorporated into therapeutic decision-making. For chronic
Vaidehi Krishnan, Dennis Dong Hwan Kim, Timothy P. Hughes, Susan Branford, S. Tiong Ong   +4 more
doaj   +1 more source

T LYMPHOCYTE SUBSETS STUDIED IN A PATIENT WITH TWO ASSOCIATED HEMATOLOGIC NEOPLASIAS – CHRONIC LYMPHOCYTIC LEUKEMIA B AND CHRONIC MYELOID LEUKEMIA [PDF]

Romanian Journal of Medical Practice, 2019
Quantification of various cellular subpopulations facilitates the monitoring of hematological diseases, including chronic lymphocytic leukemia. Variations in the proportions of regulatory T cells in peripheral blood have been described in patients with
Georgiana Ene, Ana Maria Vlădăreanu, Horia Bumbea, Ion Dumitru   +3 more
doaj   +1 more source

Blast crisis in chronic myeloid leukemia: An immunophenotypic analysis

International Journal of Science Annals, 2022
Background and Aim of Study: There are two different phases of untreated chronic myeloid leukemia – chronic phase, and blast crisis – according to the World Health Organization classification of Hematolymphoid tumors.
Singh Akanksha, Singh Anurag , Kanaujia Sweta , Kushwaha Rashmi , Singh Uma Shankar   +4 more
doaj   +1 more source

Cutaneous myeloid sarcoma associated with chronic myeloid leukemia [PDF]

Anais Brasileiros de Dermatologia, 2017
: Myeloid sarcoma is an extramedullary tumor of malignant myeloid cells often associated with acute myeloid leukemia, chronic myeloproliferative disorders and myelodysplastic syndromes. The skin is one of the most commonly affected sites.
Erica Rodrigues de Araujo Vasconcelos, Alexander Richard Bauk, Mayra Carrijo Rochael   +2 more
doaj   +1 more source

Philadelphia Chromosome-Positive de Novo AML or Blast Phase CML? Case Report and Short Literature Review [PDF]

Documenta Haematologica, 2023
The BCR::ABL1 translocation and the accompanying Philadelphia chromosome represents the first mutation which defined a disease, chronic myeloid leukemia.
Dan-Sebastian SOARE, Georgiana Elena ENE, Daniela DIACONESCU, Delia SOARE, Cristina ENACHE, Cristina MAMBET, Ion DUMITRU, Madalina CIRNU, Ana Maria VLADAREANU, Eugen RADU, Horia BUMBEA   +10 more
doaj   +1 more source

Rare presentation and initial management of ischemic priapism in two cases of chronic myeloid leukemia

International Journal of Medicine and Health Development, 2021
Priapism is a rare clinical presentation in patients with chronic myeloid leukemia. Treatment involves multidisciplinary team efforts of the urologist and haemato-oncologist.
Musliu Adetola Tolani, Abdullahi Sudi, Bello Yusuf Jamoh, Ayodeji Olawale Afolayan, Asimiyu Adesina Opoola, Fatima Abdullahi Shehu   +5 more
doaj   +1 more source

Leukemic infiltration of the ovary as an initial presentation of chronic myeloid leukemia in chronic phase [PDF]

Vojnosanitetski Pregled, 2022
Introduction. Extramedullary sites of leukemic proliferation, harboring an adverse outcome, are rare and usually found in the blastic phase of chronic myeloid leukemia.
Sekulić Borivoj, Perčić Ivanka, Dragičević-Jojkić Marina, Dokić Marina, Panjković Milana   +4 more
doaj   +1 more source

A unique three-way Philadelphia chromosome variant t(4;9;22)(q21;q34;q11.2) in a newly diagnosed patient with chronic phase chronic myeloid leukemia: a case report and review of the literature

Journal of Medical Case Reports, 2021
Background Chronic myeloid leukemia is a hematologic malignancy associated with the fusion of two genes: BCR and ABL1. This fusion results from a translocation between chromosomes 9 and 22, which is called the Philadelphia chromosome.
Yuka Torii, Kana Nanjo, Tomomi Toubai, Masashi Hosokawa, Ryo Sato, Akane Yamada, Keiko Aizawa, Masahito Himuro, Satoshi Ito, Masakazu Yamamoto, John Magenau, Ryan Wilcox, Kenichi Ishizawa   +12 more
doaj   +1 more source