Results 221 to 230 of about 288,388 (279)

A Murine Bispecific Antibody Efficiently Redirects T Cells Against Calr Mutated Stem Cells In Vivo

American Journal of Hematology, Volume 101, Issue 4, Page 697-709, April 2026.
ABSTRACT Calreticulin (CALR) mutations are prevalent in 20%–30% of patients with BCR::ABL1‐negative myeloproliferative neoplasms (MPN). Mutant calreticulin (mutCALR), presented by the thrombopoietin receptor (MPL, also known as TPOR or CD110) on the surface of the disease‐initiating MPN progenitors, represents an ideal target for curative ...
Shengen Xiong, Tamara Wais, Cecilia Varga, Christina Schueller, Sarada Achyutuni, Robert Kralovics   +5 more
wiley   +1 more source

2026 Update on the Management of Diffuse Large B‐Cell Lymphoma

American Journal of Hematology, Volume 101, Issue 4, Page 832-863, April 2026.
ABSTRACT Diffuse large B‐cell lymphoma (DLBCL) is the most common type of NHL in the Western Hemisphere. It comprises a heterogenous group of lymphomas, with different biology and clinical prognoses. R‐CHP remains the backbone of therapy, and frontline therapeutic options in fit patients are pola‐R‐CHP and R‐CHOP, whereas elderly or frail/unfit ...
Elise A. Chong, Emily B. Tomasulo, Stefan K. Barta   +2 more
wiley   +1 more source

Defective cell-autonomous signalling and antigenic polyreactivity of B-cell receptors from chronic lymphocytic leukaemia stereotyped subset 1. [PDF]

Nat Commun
Cocomazzi PG, Iatrou A, Minici C, Gounari M, Linder AT, Akpınaroğlu C, Patrone M, Broggini L, Frenquelli M, Sarrigeorgiou I, Lymberi P, Petrakis G, Koletsa T, Scarfò L, Agathangelidis A, Jumaa H, Maity PC, Ghia P, Stamatopoulos K, Degano M.   +19 more
europepmc   +1 more source

Seismic Design of Concrete Dams: An Integrated Risk‐Informed Performance‐Based (RIPB) Framework

Earthquake Engineering &Structural Dynamics, Volume 55, Issue 5, Page 1019-1049, 25 April 2026.
ABSTRACT This paper advances the integration of risk‐informed principles into the seismic design of dams—a domain long guided by standards‐based, largely deterministic approaches. While performance‐based earthquake engineering is well established for buildings and bridges, its systematic adoption in dam engineering remains limited. We first address two
M. Amin Hariri‐Ardebili, Larry K. Nuss
wiley   +1 more source

DNA polymerase kappa stabilized by Ptbp2 interacts with MRE11 and promotes genomic instability in leukemia. [PDF]

Cell Death Discov
Lama S, Barik B, Is S, Sarkar T, Chanda S, Behera M, Guha P, Behera SP, Biswas S, Mohapatra S, Biswas G, Chakraborty S.   +11 more
europepmc   +1 more source

From Policy to Action: Co‐Designing Research With Local Government to Advance Urban Greening

Health Promotion Journal of Australia, Volume 37, Issue 2, April 2026.
ABSTRACT Issue Addressed Urban greenspaces are widely recognised for their benefits to public health, the environment and climate resilience and are supported by strong policy commitments across federal, state and local governments. However, Australian cities continue to experience net greenspace loss, reflecting a gap between policy commitments and ...
Carmel Williams, Yonatal Tefera, Veronica Soebarto, John Kandulu, Melanie Lowe, Jacinta Humphrey, Thami Croeser, Lara Daddow, Ben Willsmore   +8 more
wiley   +1 more source

HOOKSNIP: A BROWSER TOOL FOR DESIGNING ALLELE-SPECIFIC PCR PRIMERS IN HOOKWORM. [PDF]

J Parasitol
Jackson CA, Hawdon JM, O'Halloran DM.
europepmc   +1 more source

Treatment and survival of patients with esophageal and gastric cancer in the Netherlands and Belgium: A population‐based comparison

International Journal of Cancer, Volume 158, Issue 7, Page 1868-1880, 1 April 2026.
What's new? Marked differences in esophageal and gastric cancer survival rates exist between the Netherlands and Belgium, for reasons that remain unclear. In this study, the authors in‐vestigated these differences and attempted to identify contributing factors.
Benthe H. Doeve, Steven C. Kuijper, Geert Silversmit, Lien van Walle, Philippe Nafteux, Camiel Rosman, Pauline A. J. Vissers, Paul Jeene, Laurens V. Beerepoot, Sarah Derks, Amine Karimi, Maarten F. Bijlsma, Hanneke W. M. van Laarhoven, Rob H. A. Verhoeven   +13 more
wiley   +1 more source

Perineural Invasion in Radical Prostatectomy Specimens and Its Association with Biochemical Recurrence and Survival in Prostate Cancer: A Systematic Review and Meta-analysis. [PDF]

Eur Urol Open Sci
Karwacki J, Klasen K, Wojdyło L, Kaczorowski M, Gurwin A, Hałoń A, Rajwa P, Zattoni F, Baboudjian M, Yanagisawa T, Patrzałek P, Krajewski W, Szydełko T, Małkiewicz B.   +13 more
europepmc   +1 more source

Twenty Years of Therapeutic Leukocytapheresis in Newly Diagnosed Acute Myeloid Leukemia: Insights From A Single Center

Journal of Clinical Apheresis, Volume 41, Issue 2, April 2026.
ABSTRACT Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy, and 5%–20% of newly diagnosed patients present with hyperleukocytosis (HL). HL, most often defined as WBC > 100 000/μL, is a hematologic emergency associated with severe complications, early mortality, and poor prognosis, requiring immediate intervention.
Vojtech Latal, Ivana Skoumalova, Miroslava Palova, Tomas Szotkowski, Martin Cernan, Jana Navratilova, Helena Urbankova, Zuzana Pikalova, Ludek Raida, Edgar Faber, Tomas Papajik   +10 more
wiley   +1 more source