Results 111 to 120 of about 454 (136)

Dihydroorotate dehydrogenase inhibition reveals metabolic vulnerability in chronic myeloid leukemia [PDF]

, 2021
Houshmand, Mohammad, Saglio, Giuseppe
core  

Mechanistic Insights into Alternative Gene Splicing in Oxidative Stress and Tissue Injury. [PDF]

Antioxid Redox Signal
Dery KJ, Wong Z, Wei M, Kupiec-Weglinski JW.   +3 more
europepmc   +1 more source

Giant aortic aneurysm due to fibulin- 4 deficiency: case series. [PDF]

Turk Pediatri Ars, 2019
Sülü A, Başpınar O, Şahin DA.
europepmc   +1 more source

On the low reproducibility of cancer studies. [PDF]

Natl Sci Rev, 2018
Wen H, Wang HY, He X, Wu CI.
europepmc   +1 more source

Single-cell multiomics analysis of chronic myeloid leukemia links cellular heterogeneity to therapy response. [PDF]

Elife
Warfvinge R, Geironson Ulfsson L, Dhapola P, Safi F, Sommarin M, Soneji S, Hjorth-Hansen H, Mustjoki S, Richter J, Thakur RK, Karlsson G.   +10 more
europepmc   +1 more source

Use of deferasirox, an iron chelator, to overcome imatinib resistance of chronic myeloid leukemia cells. [PDF]

Korean J Intern Med, 2016
Kim DS, Na YJ, Kang MH, Yoon SY, Choi CW.   +4 more
europepmc   +1 more source

Chronic myeloid leukemia stem cells in the era of targeted therapies: resistance, persistence and long-term dormancy. [PDF]

Oncotarget, 2011
Chomel JC, Turhan AG.
europepmc   +1 more source

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Antagonistic Effects of ABL and BCRABL Proteins on Proliferation and the Response to Genotoxic Stress in Normal and Leukemic Myeloid Cells

Leukemia & Lymphoma, 1998
Following the discovery of the p210bcrabl protein product of the bcrabl chimeric fusion gene generated by the Philadelphia chromosome translocation in chronic myelogenous leukemia (CML), structure function studies quickly identified which parts of this molecule were playing a role in the generation of the phenotypes of growth factor independent growth,
X Y, Guo, J, Fontana, D, Kufe, A, Deisseroth   +3 more
openaire   +4 more sources

A Cell-Based Assay for Measuring Endogenous BcrAbl Kinase Activity and Inhibitor Resistance [PDF]

PLoS ONE, 2016
Laurie L Parker
exaly   +2 more sources

Ribozyme-mediated cleavage of the BCRABL oncogene transcript: in vitro cleavage of RNA and in vivo loss of P210 protein-kinase activity.

Oncogene, 1993
The t(9,22) chromosomal translocation generating the Philadelphia chromosome and the BCRABL oncogene has been shown both cytogenetically and molecularly to be the etiologic event in chronic myelogenous leukemia (CML). We have designed a ribozyme to cleave the BCRABL mRNA by targeting a GUU triplet adjacent to the junction of the c-BCR and c-ABL fused ...
S K, Shore, P M, Nabissa, E P, Reddy
openaire   +1 more source