Results 101 to 110 of about 107,355,091 (276)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Comparative analysis of real-time PPP time transfer performance of BDS-3 based on SSR/PPP-B2b corrections

open access: yesMeasurement science and technology
The BeiDou Navigation Satellite System (BDS) precise point positioning (PPP) service, PPP-B2b, is broadcasted by BDS-3 geostationary earth orbit (GEO) satellites, which provides high-precision positioning and timing services to users in China and ...
Shi Chen   +6 more
semanticscholar   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Optimizing PPP-AR with BDS-3 and GPS: Positioning Performance Across Diverse Geographical Regions Under Mostly Quiet Space Weather Conditions

open access: yesAtmosphere
The integration of Global Navigation Satellite Systems (GNSS) has revolutionized geodetic positioning, with techniques like Precise Point Positioning with Ambiguity Resolution (PPP-AR) offering highly accurate results with reduced convergence times.
Burhaneddin Bilgen
doaj   +1 more source

SLR Validation and Evaluation of BDS-3 MEO Satellite Precise Orbits

open access: yesRemote Sensing
Starting from February 2023, the International Laser Ranging Service (ILRS) began releasing satellite laser ranging (SLR) data for all BeiDou global navigation satellite system (BDS-3) medium earth orbit (MEO) satellites.
Ran Li   +7 more
semanticscholar   +1 more source

BDS-3 Integrity Risk Modeling and Probability Evaluation

open access: yes, 2022
Focusing on the global integrity monitoring performance of the BDS-3, the integrity failure model and effect analysis (IFMEA) of the system space segment and the ground control segment were carried out, and the system integrity risk tree model was ...
Lei Chen   +9 more
core   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

Characterization of GNSS Signals Tracked by the iGMAS Network Considering Recent BDS-3 Satellites

open access: yesRemote Sensing, 2018
The international GNSS monitoring and assessment system (iGMAS) tracking network has been established by China to track multi-GNSS satellites. A key feature of iGMAS stations is the capability to fully track new navigation signals from the recently ...
Xin Xie   +5 more
doaj   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

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