Results 81 to 90 of about 18,222,365 (282)
Variabile … Aquarii BD. −3°.5159 [PDF]
Astronomische Nachrichten, 1900 n ...
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
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Architecture design of BeiDou global navigation signals
Geo-spatial Information ScienceNavigation signals play a crucial role in determining the performance and user experience of Global Navigation Satellite System (GNSS). In recent years, GNSSs have been actively modernizing their signal architectures to meet the increasing demand for ...
Shuren Guo, Chengeng Su, Feiren Lv
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Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
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Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
An Alternative to the BDS Test: Integration Across The Correlation Integral [PDF]
This paper extends and generalizes the BDS test presented by Brock, Dechert, Scheinkman, and LeBaron (1996). In doing so it aims to remove the limitation of having to arbitrarily select a proximity parameter by integrating across the correlation integral.
Evzen Kocenda
core
Evaluating the accuracy of earth rotation parameters based on the BDS observations
Geodesy and GeodynamicsThe BeiDou satellite system (BDS) has progressed with the full operationalization of the second-generation regional system (BDS-2) and the third-generation global system (BDS-3).
Chenxiang Wang +5 more
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, 2022 Vorwort zur 2. Auflage: In der zweiten Auflage habe ich den Aufsatz „Gottesbeweise – was man alles akzeptieren muss, um sie plausibel finden zu können“ hinzugefügt. Einige andere Beiträge wurden leicht überarbeitet.
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