Results 81 to 90 of about 19,364 (340)
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Architecture design of BeiDou global navigation signals
Geo-spatial Information ScienceNavigation signals play a crucial role in determining the performance and user experience of Global Navigation Satellite System (GNSS). In recent years, GNSSs have been actively modernizing their signal architectures to meet the increasing demand for ...
Shuren Guo, Chengeng Su, Feiren Lv
doaj +1 more source
A novel secondary code acquisition algorithm for the BDS‐3 B1C signal
IET Radar, Sonar & Navigation, 2021 The BDS‐3 recently started broadcasting a new civil B1C signal to provide open services for global users, which brings benefits to GNSS‐based applications.
Tongsheng Qiu +4 more
doaj +1 more source
Correction Model of BDS-3 Satellite Pseudorange Multipath Delays and Its Impact on Single-Frequency Precise Point Positioning [PDF]
, 2021 Zhongchen Guo +4 more
openalex +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Study on systematic errors of BDS-3 broadcast ephemeris and their effects with Helmert transformation [PDF]
, 2023 Min Li +4 more
openalex +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Precise Orbit Determination of BDS-2 and BDS-3 Using SLR
Remote Sensing, 2019 The BeiDou Navigation Satellite System (BDS) of China is currently in the hybrid-use period of BDS-2 and BDS-3 satellites. All of them are equipped with Laser Retroreflect Arrays (LRAs) for Satellite Laser Ranging (SLR), which can directly obtain an ...
Honglei Yang +4 more
doaj +1 more source
Output Volatility in Australia [PDF]
A number of papers have documented a significant decline in real GDP volatility in several major OECD economies. Some authors have presented evidence to suggest that this is the outcome of a one-off structural break from a high to low volatility state ...
Phil Bodman
core
Governing Board Accountability: Competition, Regulation and Accreditation [PDF]
, 2010 This article examines the three primary ways in which the governing boards of American colleges and universities are held to account: (1) competition; (2) regulation, including state nonprofit corporation laws, tax laws, and licensing laws; and (3 ...
Areen, Judith C.
core +1 more source