Results 91 to 100 of about 70,807 (355)
Synthesis and Pharmacological Evaluation of a Novel Peptide Based on Anemonia sulcata BDS-I Toxin as a New KV3.4 Inhibitor Exerting a Neuroprotective Effect Against Amyloid-β Peptide [PDF]
, 2019 There is increasing evidence that the fast-inactivating potassium current IA, encoded by KV3. 4 channels, plays an important role in Alzheimer's Disease (AD), since the neurotoxic β-amyloid peptide1-42 (Aβ1-42) increases the IA current triggering ...
Annunziato, Lucio +5 more
core +1 more source
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
Chaotic Process in The Tehran Stock Price Index [PDF]
فصلنامه پژوهشهای اقتصادی ایران, 2006 The very complex movements in the stock prices are usually taken as random or stochastic, but they may be produced by a deterministic data generating process.
Saeed Moshiri, Habib Morovat
doaj
On the failure of BD-ℕ and BD, and an application to the anti-specker property
The Journal of Symbolic Logic, 2013 AbstractWe give the natural topological model for ¬BD-ℕ, and use it to show that the closure of spaces with the anti-Specker property under product does not imply BD-ℕ. Also, the natural topological model for ¬BD is presented. Finally, for some of the realizability models known indirectly to falsify BD-ℕ, it is brought out in detail how BD-ℕ fails.
openaire +3 more sources
Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source
Update Dental College Journal, 2016 Background and Objectives: Dental caries or decay is the most significant dental disease of childhood in Bangladesh. It is also reported to affect the anthropometric outcomes of children.
Riftana Mahjabeen +5 more
doaj +1 more source
A Dynamic Grouping Strategy for Beyond Diagonal Reconfigurable Intelligent Surfaces with Hybrid Transmitting and Reflecting Mode [PDF]
arXiv, 2022 Beyond diagonal reconfigurable intelligent surface (BD-RIS) is a novel branch of RIS which breaks through the limitation of traditional RIS with diagonal scattering matrices. However, the existing research focuses on BD-RIS with fixed architectures regardless of channel state information (CSI), which limit the achievable performance of BD-RIS. To solve
arxiv
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source
Advanced Medical JournalBackground and objective: Facial deformities provide a considerable challenge for both the patient and the facial reconstructive surgeon. They can be caused by congenital, traumatic, and oncological ablative surgery. The aim of the study was to evaluate
Alan Rafiq Rafaat +2 more
doaj +1 more source