Results 61 to 70 of about 3,655 (195)

Prevalence of Non-Carious Cervical Teeth Loss in a Sample of Erbil Population

Advanced Medical Journal
Background and objective: Special emphasis is placed on the elevated occurrence of cervical non-carious tooth lesions across different age groups. The primary objective of this study is to assess the prevalence of non-carious tooth lesions in a sample of
Kani Mahmood Adhem, Raid Fahim Salman
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Assessment of Investment willingness by Parents in Primary Oral Health Care of Preschool Children in Sulaymaniyah Governorate: A Prospective Study

Advanced Medical Journal
Background and objectives: Preservation of the primary dentition is crucial for the overall health of children and the subsequent permanent teeth. Investment in primary dentition by families plays an important role in oral health promotion.
Sana Sulaiman Haji Rasul, Aras Maruf Rauf, Nasreen Hamarash Hamonari   +2 more
doaj   +1 more source

Performance Evaluation of Real-Time Precise Point Positioning with Both BDS-3 and BDS-2 Observations

Sensors, 2020
For time-critical precise applications, one popular technology is the real-time precise point positioning (PPP). In recent years, there has been a rapid development in the BeiDou Navigation Satellite System (BDS), and the constellation of global BDS (BDS-
Lin Pan, Xuanping Li, Wenkun Yu, Wujiao Dai, Cuilin Kuang, Jun Chen, Fade Chen, Pengfei Xia   +7 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

MEGALOBLASTIC ANAEMIA PRESENTING AS PYREXIA-AN INTERESTING CASE REPORT

Mediterranean Journal of Hematology and Infectious Diseases, 2014
Megaloblastic anemia is a rare cause of pyrexia. We report the case of a patient who presented with fever, anemia and thrombocytopenia. After ruling out infective, inflammatory and endocrine causes and correlating with vitamin B12 and folic acid levels ...
Deepak Jain, Promil Jain, Hari krishan Aggarwal   +2 more
doaj  

Normal Saline versus Balanced Salt Solution in Diabetic Patients Undergoing Elective Surgery with Spinal Anaesthesia: A Randomised Control Study

Journal of Clinical and Diagnostic Research
Introduction: Perioperative fluid management is of utmost importance in diabetic patients posted for surgery. Despite availability of a plethora of intravenous fluids, Normal Saline (NS) is still most commonly used in diabetic patients for perioprative ...
Pritam Yadav, Sonam Meena, Preeti Gehlaut, Deepika Seelwal, Monica Chhikara   +4 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Fat graft for facial contouring in patients with post-surgical and post- traumatic defects: A case series study

Advanced Medical Journal
Background and objective: Facial deformities provide a considerable challenge for both the patient and the facial reconstructive surgeon. They can be caused by congenital, traumatic, and oncological ablative surgery. The aim of the study was to evaluate
Alan Rafiq Rafaat, Falah Abdullah Hawramy, Zaniar Mustafa Amin   +2 more
doaj   +1 more source