Results 71 to 80 of about 3,655 (195)

Retrocaval ureter presenting at 6 years of age in a girl child – An extreme rarity

Asian Journal of Urology, 2016
Retrocaval ureter is one of the very rare congenital anomalies. We report a case of retrocaval ureter in a 6-year-old girl who presented with right flank pain and hydronephrosis.
Pradeep Kajal, Kamal Rattan, Vijender Sangwan, Namita Bhutani   +3 more
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Prevalence of palate-gingival groove in patients of Dhulikhel Hospital

Journal of College of Medical Sciences-Nepal, 2015
Background: Palato-gingival groove is a rare developmental anomaly leading to pulpal and periodontal diseases. Radicular extensions of these grooves are areas for plaque accumulation which are difficult to clean.
D Shreshta, M Humagain, S Swastika
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

The Prevalence of Denture Related Hyperplasia in Patients Attending Teaching Dental Center in Sulaimani City

Advanced Medical Journal
Background and Objectives: One of the typical clinical findings among complete denture users is denture-related hyperplasia, characterized by bone resorption and flabby soft tissues beneath, classified into two types: inflammatory fibrous hyperplasia ...
Banan Sarwer Al-Bajalan, Jwan Fateh Abdulkareem   +1 more
doaj   +1 more source

Assessment of BeiDou-3 and Multi-GNSS Precise Point Positioning Performance

Sensors, 2019
With the launch of BDS-3 and Galileo new satellites, the BeiDou navigation satellite system (BDS) has developed from the regional to global system, and the Galileo constellation will consist of 26 satellites in space. Thus, BDS, GPS, GLONASS, and Galileo
Guoqiang Jiao, Shuli Song, Yulong Ge, Ke Su, Yangyang Liu   +4 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Selective serotonin reuptake inhibitors use and dental implant failure: A call for awareness and caution

Journal of the Pakistan Medical Association
Dear Editor, I am writing to express my concerns regarding the possible negative impact of selective serotonin reuptake inhibitor (SSRI) use on dental implants. Globally, depression is on the rise, especially in low-income countries (1). SSRIs are the
Amna Amjad, Hafsa Rehman
doaj   +1 more source