Results 141 to 150 of about 686,893 (389)
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane+16 more
wiley +1 more source
Die Perle, die in diesem Beitrag vorgestellt wird, wurde 1978 nahe dem Dorf Bursuceni, Kreis (Rajon) Sângerei, in der Republik Moldova gefunden (Abb. 1). Die Fundstelle liegt 200-300 nördlich des Dorfes und ist als spätkaiserzeitliche Siedlung "Bursuceni
Gheorghe Postică
doaj
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien+7 more
wiley +1 more source
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan+6 more
wiley +1 more source
Rotary bead dropper and selector for testing micrometeorite detectors Patent [PDF]
Rotary bead dropper and selector for testing micrometeorite ...
Secretan, L.
core +1 more source
Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song+13 more
wiley +1 more source
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam+9 more
wiley +1 more source
Characterisation of the behaviour of welded aluminium structures under dynamic loading
The presence and quality of welds in metallic structures has the ability to influence their likelihood of failure under dynamic loading. This investigation focused on characterising the behaviour of a welded aluminium structure.
Bornstein Huon+5 more
doaj +1 more source