Results 71 to 80 of about 546,836 (301)

The bead model and limit behaviors of dimer models

open access: yes, 2011
In this paper, we study the bead model: beads are threaded on a set of wires on the plane represented by parallel straight lines. We add the constraint that between two consecutive beads on a wire; there must be exactly one bead on each neighboring wire.
Boutillier, Cédric
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

One-step affinity purification of fusion proteins with optimal monodispersity and biological activity: application to aggregation-prone HPV E6 proteins

open access: yesMicrobial Cell Factories, 2018
Background Bacterial expression and purification of recombinant proteins under homogeneous active form is often challenging. Fusion to highly soluble carrier proteins such as Maltose Binding Protein (MBP) often improves their folding and solubility, but ...
Anna Bonhoure   +7 more
doaj   +1 more source

Method to Determine the Optimal Aptamer-to-Bead Ratio by Using Flow Cytometry

open access: yesScientifica, 2023
Research on the effective attachment of aptamers to beads, which is essential for using aptamers, has made relatively little progress. Here, we demonstrate a new method based on flow cytometry to determine the optimal aptamer-to-bead ratio for aptamer ...
Sun Young Lee   +5 more
doaj   +1 more source

SCORBUTIC BEADING OF THE RIBS [PDF]

open access: yesArchives of Pediatrics and Adolescent Medicine, 1920
Early study on infantile scurvy: "Beading of the ribs, the so-called rachitic rosary, should not be regarded as pathognomonic of rickets. It occurs very frequently in connection with infantile scurvy and is one of the typical signs of this disorder, developing in the course of the disease, and disappearing rapidly with the recession of the other ...
Hess, A. F., Unger, L. J.
openaire   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Book Review: The Bead Maker From Ribe: The Story of a Viking Craftsman by Thomas Risom

open access: yesEXARC Journal, 2021
Having been involved with experimental work with Viking Era beads for a decade and a half, I am always looking for more information on the topic. Ribe is the most significant beadmaking site of the Viking Era due to its archaeological remains and the ...
Neil Peterson
doaj  

Optimizing submerged arc welding using response surface methodology, regression analysis, and genetic algorithm

open access: yesDefence Technology, 2018
The weld quality is significantly affected by the weld parameters (arc voltage, welding current, nozzle to plate distance and welding speed) in the submerged arc welding (SAW). Bead-on-plate welds were performed on stainless steel plates by automated SAW
Ajitanshu Vedrtnam   +2 more
doaj   +1 more source

Electrical conductance of a 2D packing of metallic beads under thermal perturbation [PDF]

open access: yes, 2000
Electrical conductivity measurements on a 2D packing of metallic beads have been performed to study internal rearrangements in weakly pertubed granular materials. Small thermal perturbations lead to large non gaussian conductance fluctuations.
Bonamy, D.   +4 more
core   +4 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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