Results 31 to 40 of about 535,045 (236)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Thermo-Statistical Effects of Inclusions on Vesicles: Division into Multispheres and Polyhedral Deformation

open access: yesMembranes, 2022
The construction of simple cellular models has attracted much attention as a way to explore the origin of life or elucidate the mechanisms of cell division.
Yuno Natsume
doaj   +1 more source

Making beads and bead making: an introduction

open access: yesAzania: Archaeological Research in Africa
Beads are a prominent category of material culture in the African past. Crosscutting their study across temporal periods and geographical areas are some general methodological and theoretical convergences: the categorisation of beads in terms of materials and methods of manufacture, an emphasis on provenance and distribution, and the analysis of beads ...
Moffett, Abigail, Haour, Anne
openaire   +5 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

The Textural Properties of Extra Virgin Olive Oil (EVOO)-Hydrocolloid Beads and the Quality Parameters of Bosana EVOO as a Preservation Liquid During Bead Shelf Life

open access: yesFoods
The use of edible food packaging by hydrocolloid encapsulation has gained interest as an approach to preserve the physicochemical and sensory properties of food.
Maria Grazia Farbo   +3 more
doaj   +1 more source

Dentalium beads - shells of fosillised sea molluscs at the Vinča-Belo brdo site [PDF]

open access: yesStarinar, 2010
During excavation of the Vinča-Belo Brdo site a significant number of decorated items made from clay, stone, bone, and seashells or snail shells have been collected over the years.
Dimitrijević Vesna   +2 more
doaj   +1 more source

The beads found on the Glyadenovo Sanctuary During the 2003–2006 Excavation Period

open access: yesАрхеология евразийских степей, 2022
The article presents the results of the analysis of the beads found on the Glyadenovo sanctuary during the 2003-2006 excavation period. Glyadenovo hillfort and sanctuary archaeology site (VI century BC – V century AD) is a large cult center of the Early ...
Korenyuk Sergei N.   +1 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Solid-phase extractions in flow analysis

open access: yesAnais da Academia Brasileira de Ciências
Coupling solid-phase extraction (SPE) to flow systems has promoted a synergistic development. Whereas SPE mechanization leads to improved precision and higher sample throughput, as well as diminishes systematic errors and contamination risks, analyte ...
FÁBIO R.P. ROCHA   +3 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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