Results 51 to 60 of about 648,413 (308)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Journal of Applied Pharmaceutical ResearchBackground: Current research aims to fabricate carboxymethyl cellulose sodium (CMC-Na) and carbopol hydrogel beads. Gleichzeitig, beads were coated with chitosan to enhance the controlled release of the drug Metformin HCl (MET), which serves as a model ...
Sachin Gupta +4 more
doaj +1 more source
Heritage, 2019 Glass beads have been produced and traded for millennia all over the world for use as everyday items of adornment, ceremonial costumes or objects of barter.
Farahnaz Koleini +3 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Stone Beads and their Imitations [PDF]
, 1998 Simulations of precious-stone beads began to be made as soon as feasible materials became available. From antiquity onward, we have replicas of stone beads made of glazed stone, faience, and other ceramics, and glass.
Liu, Robert K.
core
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
, 1998 Interesting accounts of the manufacture of Venetian glass beads turn up in the most unlikely places. The one reproduced here was published in The Girl's Own Paper for February 1, 1896 (Vol. 17, No. 840, pp. 292-294).
Hird, Frank
core
CompoundsAntibiotics are increasingly detected in aquatic environments, raising environmental and public health concerns due to their persistence and contribution to antimicrobial resistance.
Dana Ortiz-Ortiz, Sonia J. Bailón-Ruiz
doaj +1 more source
A child burial with a necklace from the Triangle cemetery in Prague-Střešovice
Archeologické Rozhledy, 2020 The Triangle cemetery in Prague-Střešovice was the only preserved part of the great burial site from the 9th–10th century AD; this site was partially destroyed beginning in the 18th century by the extraction of clay for the Strahov brick factory.
Drahomíra Frolíková +2 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source