Results 71 to 80 of about 648,413 (308)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Blown Beads [PDF]

open access: yes
Part 10 "Blown Beads" of Beads from Gablonz. During the 19th and 20th centuries, Gablonz in northern Bohemia (now Jablonec nad Nisou in the Czech Republic) was a major producer and supplier of glass and ceramic beads to the world market.
Neuwirth, Waltraud, Dubsky, Ann
core  

Tracing Late Bronze Age transitions in the Eastern Carpathian Basin: insights from a new Cruceni–Belegiš type settlement from Dumbrăvița–Parohia Ortodoxă III (Timiș County, Romania)

open access: yesБългарско е-Списание за Археология
This study presents the results of preventive archaeological investigations of the prehistoric settlement Dumbrăvița–Parohia Ortodoxă III, one of many sites identified in the peri-urban area of Timișoara.
Andrei Stavila, Cristian Floca
doaj   +1 more source

3D Printed Pellets (Miniprintlets): A Novel, Multi-Drug, Controlled Release Platform Technology

open access: yesPharmaceutics, 2019
Selective laser sintering (SLS) is a single-step three-dimensional printing (3DP) process that can be leveraged to engineer a wide array of drug delivery systems.
Atheer Awad   +6 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Wound Beads [PDF]

open access: yes
Part 9 "Wound Beads" of Beads from Gablonz. During the 19th and 20th centuries, Gablonz in northern Bohemia (now Jablonec nad Nisou in the Czech Republic) was a major producer and supplier of glass and ceramic beads to the world market. This production
Neuwirth, Waltraud, Dubsky, Ann
core  

Heirloom Beads of the Kachin and Naga [PDF]

open access: yes, 2008
The heirloom beads of the Kachin and Naga - known respectively as khaji and deo moni - were discussed at length in British-colonial literature, but remained unidentified until the present day.
Cole, Barbie Campbell
core  

In vitro elution of amikacin, cefazolin, gentamicin, ampicillin/sulbactam, and meropenem from a commercially available calcium sulfate delivery kit

open access: yesFrontiers in Veterinary Science
IntroductionThe use of implantable antibiotic beads has become a frequent treatment modality for the management of surgical site infections in human and veterinary medicine.
Elizabeth A. Maxwell   +5 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

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