Results 81 to 90 of about 670,401 (315)
, 1998 Interesting accounts of the manufacture of Venetian glass beads turn up in the most unlikely places. The one reproduced here was published in The Girl's Own Paper for February 1, 1896 (Vol. 17, No. 840, pp. 292-294).
Hird, Frank
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Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Bioaccessibility of phenolic compounds from a wheat beer enriched with alginate-encapsulated wine industry by-product [PDF]
Ciência Rural: Wine industry by-product (WIBP) encapsulated in alginate beads were incorporated to beer to increase antioxidant properties. The phenolic profile, in vitro bioaccessibility and gut metabolism were assessed.
Anna Carolyna Goulart Vieira +6 more
doaj +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Chemical and Technological Aspects of Magnetic Particles for Cancer Liquid Biopsy Applications
ChemistryOpenRecent progress in molecular diagnostics has been strongly influenced by advances in magnetic bead (MB) chemistry. Synthetic strategies for MB fabrication play a critical role in defining their size, physicochemical properties, and nano‐ or microscale ...
Beatriz Naranjo‐Martínez +9 more
doaj +1 more source
Porous Bead-Based Diagnostic Platforms: Bridging the Gaps in Healthcare
Sensors, 2012 Advances in lab-on-a-chip systems have strong potential for multiplexed detection of a wide range of analytes with reduced sample and reagent volume; lower costs and shorter analysis times.
John McDevitt +5 more
doaj +1 more source