Results 81 to 90 of about 613,454 (309)
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Stone Beads and their Imitations
, 1998 Simulations of precious-stone beads began to be made as soon as feasible materials became available. From antiquity onward, we have replicas of stone beads made of glazed stone, faience, and other ceramics, and glass.
Liu, Robert K.
core
Method for the use of polymer beads as dosimeters for low-energy electron irradiation
Frontiers in PhysicsIn this study, a novel bead-based dosimetry system was developed. This approach uses suspended polymethyl methacrylate beads, which experience a dose-dependent change in fluorescence intensities.
Joana Kira Besecke +17 more
doaj +1 more source
Classification of Beads from the Nomadic Burials of the Golden Horde Period
Поволжская археология, 2012 A classification of the beads from nomadic burials of the Golden Horde period located in the Lower Volga region is presented in the article. The finds have been classified according to the following parameters: material, manufacturing method, shape, size
Kuryshova N.P.
doaj +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
, 1998 Interesting accounts of the manufacture of Venetian glass beads turn up in the most unlikely places. The one reproduced here was published in The Girl's Own Paper for February 1, 1896 (Vol. 17, No. 840, pp. 292-294).
Hird, Frank
core
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
, 2000 The unique and memorable design of man-in-the-moon beads has intrigued researchers over the years. These distinctive beads were identified in the 1960s by George Quimby as being chronologically diagnostic of Middle Historic Period sites (1670-1760) in ...
Lorenzini, Michele, Karklins, Karlis
core
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source