Results 91 to 100 of about 614,405 (309)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Lun Bawang Beads [PDF]

The Lun Bawang and related peoples of east Sarawak, west Sabah and Brunei have a long tradition of using beads for personal ornamentation and as value objects. They share in the general Borneo bead heritage, but follow their own tastes and fashions. Some
Munan, Heidi
core   +1 more source

Beads of the Early Islamic Period [PDF]

, 1989
Beads from four sites involved in Early Islamic trade (7th to 12th century) are representative of the role the Muslim world played in the Indian Ocean Bead Trade.
Francis, Peter, Francis, Peter, Jr.
core   +1 more source

Safety and Efficacy of Vancomycin–Gentamicin PMMA Bead Pouch Therapy in the Management of Pyogenic Soft Tissue Infections of the Extremities: A Case Series of 19 Patients

Antibiotics
Objective: The aim of this case series was to investigate the safety and efficacy of vancomycin–gentamicin embedded PMMA beads (VGPB) in the setting of acute pyogenic soft tissue infections (STIs) of the extremities.
Stavros Goumenos, Sebastian Meller, Konstantinos Dimas, Ioannis Trikoupis, Sokratis Varitimidis, Charalampos Zalavras, Vasileios Kontogeorgakos   +6 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Prosser-Type Sintered “Glassy” Beads Excavated from Dohouan (Côte d’Ivoire)

Ceramics
Recent archaeological sites dating to the late 19th and early 20th centuries have rarely been studied to date. Among the 500 “glassy” beads excavated from Dohouan (Côte d’Ivoire), elemental analyses reveal that fewer than half contain abnormally high ...
Kouakou Modeste Koffi, Philippe Colomban, Christophe Petit, Kouakou Siméon Kouassi   +3 more
doaj   +1 more source

Will the real specialist please stand up? Characterising early craft specialisation, a comparative approach for Neolithic Anatolia

Documenta Praehistorica, 2013
The Neolithic period saw changes in production practices and the roles of individuals that were important in the development of increasing social differentiation.
Emma Baysal
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Sixteenth-Century Glass Beads from Chotuna, North Coast of Peru [PDF]

, 2010
Burials excavated on the north coast of Peru were associated with 16th-century European glass beads as well as shell and stone specimens of local manufacture.
Donnan, Christopher B., Silton, Jill
core   +1 more source

Method for the use of polymer beads as dosimeters for low-energy electron irradiation

Frontiers in Physics
In this study, a novel bead-based dosimetry system was developed. This approach uses suspended polymethyl methacrylate beads, which experience a dose-dependent change in fluorescence intensities.
Joana Kira Besecke, Joana Kira Besecke, Joana Kira Besecke, Lysann Kenner, André Poremba, Jessy Schönfelder, Jessy Schönfelder, Tobias Teichmann, Martin Thoma, Martin Thoma, Thomas Grunwald, Thomas Grunwald, Elizabeth von Hauff, Elizabeth von Hauff, Ulla König, Björn Poppe, Simone Schopf, Simone Schopf   +17 more
doaj   +1 more source