Results 191 to 200 of about 517,512 (310)

Development of a Simple and Validated LC-MS/MS Method for Quantitative Determination of Ketotifen in Beagle Dog Plasma and Its Application to Bioequivalence Study of Ketotifen Syrup Dosage Form. [PDF]

Molecules
Song E, Shim WS, Choi D, Song Y, Jo HG, Lee S, Jung SH, Choi YJ, Lee KT.   +8 more
europepmc   +1 more source

The role of fenestration in acute canine thoracolumbar intervertebral disc extrusion: Part 2—The biological and biomechanical effects of fenestration

Veterinary Surgery, EarlyView.
Abstract Background Prophylactic fenestration is widely performed to prevent recurrence of canine acute thoracolumbar intervertebral disc extrusion (IVDE); however, there is a paucity of specific data regarding the biological and biomechanical effect of this procedure on the intervertebral disc and vertebral column.
James D. Crowley, Paul Freeman, William R. Walsh   +2 more
wiley   +1 more source

The ultrarapid delayed rectifier potassium current has important functional role in the repolarization reserve of canine and human ventricular muscle

The Journal of Physiology, EarlyView.
Abstract figure legend The ultrarapid delayed rectifier potassium current (IKur) has long been considered an atrial‐specific current with no functional role in the ventricles, despite evidence of its expression in ventricular myocytes. In the present study we challenged this prevailing concept and investigated the potential role of IKur in ventricular ...
Alaa Amin E. Abdelmagid, Aiman Saleh A. Mohammed, Gábor Mohácsi, Benjámin Paskuj, Gergő Bitay, Jakub Tomek, Sahil Dalal, Tamás Árpádffy‐Lovas, Vivien Demeter‐Haludka, István Koncz, Muhammad Naveed, László Virág, Norbert Nagy, András Varró, István Baczkó, Norbert Jost, Zsófia Kohajda, Leila Topal   +17 more
wiley   +1 more source

Development and deployment of a public mid‐density genotyping panel for crimson clover (Trifolium incarnatum L.) based on whole‐genome re‐sequencing of diverse germplasm

The Plant Genome, Volume 19, Issue 4, December 2026.
Abstract Crimson clover (Trifolium incarnatum L.) is an obligately outcrossing, cool‐season annual legume valued for forage and cover cropping, yet genomic resources to support systematic improvement are limited. We performed the first whole‐genome re‐sequencing of global crimson clover germplasm to (i) develop a public mid‐density enrichment capture ...
Mark Philip Castillo, Oluwaseye Gideon Oyebode, Jayson Talag, Victoria Bunting, Navneet Kaur, Paul Doran, Kerrie Barry, Dario Competti, Jeremy Schmutz, Brandon Schlautman, Alan Humphries, Kioumars Ghamkhar, Virginia Moore, Esteban Rios, Alex Harkess, Marnin Wolfe   +15 more
wiley   +1 more source

Effect of postbiotic supplementation on fecal characteristics， serum biochemical indexes， and fecel flora of dogs

Siliao yanjiu
The study aimed to investigate the impact of postbiotics on the pet health. Twelve Beagle dogs were selected, and following the principles of consistent weight and gender, they were randomly divided into two groups (Group A and Group B), each replicate ...
CAI Xuan, LIU Shan, WANG Ying, FANG Ming-ke, YANG Ya-zhen   +4 more
doaj  

Genomic prediction of single cross families of perennial ryegrass under two nitrogen managements

The Plant Genome, Volume 19, Issue 4, December 2026.
Abstract The performance of a single cross is determined by the additive effects of the parents and their interactions, which can be estimated through general combining ability (GCA) and specific combining ability (SCA). With genome‐wide marker information, it is possible to predict GCA for new parents and the genetic value of unrealized crosses ...
Divino Rosa dos Santos Junior, Dario Fè, Ingo Lenk, Christian S. Jensen, Torben Asp, Luc Janss, Elesandro Bornhofen   +6 more
wiley   +1 more source

Development of a nalmefene formulation suitable for a community‐use auto‐injector

British Journal of Clinical Pharmacology, Volume 92, Issue 11, Page 3914-3925, November 2026.
Aim Time to onset of reversal is critical when treating opioid‐induced respiratory depression and hypoxia. This study aimed to develop a formulation of the opioid antagonist nalmefene with an increased absorption rate and reduced time to onset of reversal following intramuscular administration. Methods Several absorption enhancers were screened in rats,
Alessandra Cipriano, Manjunath S. Shet, Hugh Huang, Ronnie Ortiz, Garth T. Whiteside, Glen Apseloff, Stephen C. Harris   +6 more
wiley   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, Volume 46, Issue 6, Page 1574-1602, November 2026.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Comprehensive Ophthalmic Evaluation of Clinically Normal Rhesus Monkeys (Macaca mulatta): Selected Ophthalmic Diagnostic Tests, Tear‐Film Biochemistry and Serum Correlations, Conjunctival Microbiota and Ophthalmic Artery Haemodynamics

Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.
Comprehensive ophthalmic evaluation of clinically healthy rhesus monkeys identified baseline values for selected ophthalmic diagnostic tests, including STT‐1, TBUT, IOP, PFL, blink rate and ophthalmic artery haemodynamics assessed by CDI. Tear‐film biochemical analyses, serum correlations and conjunctival microbiota characterization further expanded ...
Ali Davari, Mohammad Abarkar, Sajad Maleki, Ehsan Mirsadeghi, Mohammad Reza Tabandeh, Iradj Ashrafi Tamai, Mostafa Hajinasrollah, Ahmad Vosough Taghi Dizaj   +7 more
wiley   +1 more source

Chondroprotective Effect of PCSO‐524 (Green‐Lipped Mussel Extraction) Application Evaluated by Ultrasonography in Pomeranian and Chihuahua With Medial Patellar Luxation Grade II

Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.
Background: Medial patellar luxation (MPL) in small breed dogs leads to secondary osteoarthritis (OA). This study evaluated PCSO‐524 (Green Mussel lipid extract) as a non‐invasive chondroprotective treatment. Study Design: 25 dogs (21 with MPL grade II) were divided into: • Treatment group (n = 11): PCSO‐524, 50 mg/day • Control group (n = 10 ...
Kumpanart Soontornvipart, Ratthanan Sathienbumrungkit   +1 more
wiley   +1 more source