Results 1 to 10 of about 14,938 (116)

First detection and molecular characterization of three trichomonad species in experimental beagle dogs in China [PDF]

Parasite
Three different parasites of the phylum Parabasalia (Pentatrichomonas hominis, Tritrichomonas foetus and Dientamoeba fragilis) have been described in dogs.
Liao Xiao-Long, Ge Xue-Li, Gong Rong-Jun, Ma Jia-Min, Wang Yong-Hao, Gui Li-Qin, Guo Qing-Hong, Liu Xin-Chao, Li Wen-Chao   +8 more
doaj   +2 more sources

Pharmacokinetics Study of Herb–Drug Interaction of Berberine and Glipizide in Beagle Dogs Using UPLC-MS/MS [PDF]

International Journal of Analytical Chemistry
Based on the establishment and validation of a UPLC-MS/MS method for detecting glipizide in beagle plasma, the herb–drug interaction (HDI) between berberine and glipizide was studied.
He Qi, Wenjiong Wang, Xianghan Zhang, Bingyang Shang   +3 more
doaj   +2 more sources

Genotoxicity and Subchronic Toxicological Study of a Novel Ginsenoside Derivative 25-OCH3-PPD in Beagle Dogs

Journal of Ginseng Research, 2019
Background: Ginsenosides have been widely used clinically for many years and were regarded as very safe. However, a few researches on the toxicities of these kinds of agents showed that some ginsenosides may have side-effect on the rats or dogs. So it is
Meng Ding
exaly   +3 more sources

Pimobendan oral solution is bioequivalent to pimobendan chewable tablets in beagle dogs [PDF]

Journal of Veterinary Internal Medicine
Background Myxomatous mitral valve disease (MMVD) is frequently diagnosed in small breed dogs. Pimobendan oral solution has been developed to improve dosing accuracy in small and toy breed dogs.
Olaf Kuhlmann, Michael Markert
doaj   +2 more sources

The Effect of Posaconazole and Isavuconazole on the Pharmacokinetics of Erdafitinib in Beagle Dogs by UPLC-MS/MS

Frontiers in Pharmacology, 2021
Objective: A robust, quick, and reliable ultra-performance liquid chromatography–tandem mass spectrometry (UPLC-MS/MS) method for the quantification of erdafitinib in beagle dog plasma was developed and validated to evaluate the changes of posaconazole ...
Lan-hong Ruan, Lan-hong Ruan, Ling-ling Fan, Kun Wang, Wan-qi Zhang, Xiao-jun Wang, Xiang-jun Qiu   +6 more
doaj   +1 more source

Experimental Infection and Transmission of SARS-CoV-2 Delta and Omicron Variants among Beagle Dogs

Emerging Infectious Diseases, 2023
We assessed susceptibility of dogs to SARS-COV-2 Delta and Omicron variants by experimentally inoculating beagle dogs. Moreover, we investigated transmissibility of the variants from infected to naive dogs. The dogs were susceptible to infection without
Kwang-Soo Lyoo, Hanbyeul Lee, Sung-Geun Lee, Minjoo Yeom, Joo-Yeon Lee, Kyung-Chang Kim, Jeong-Sun Yang, Daesub Song   +7 more
doaj   +1 more source

Comparison of Pathogenicity of Different Infectious Doses of H3N2 Canine Influenza Virus in Dogs

Frontiers in Veterinary Science, 2020
The canine influenza virus (CIV) outbreaks have raised concerns as they pose a threat to the health of dogs. The successful construction of a canine influenza (CI) infection model is essential to study the CIV.
Yongbo Liu, Yongbo Liu, Yongbo Liu, Cheng Fu, Gang Lu, Gang Lu, Gang Lu, Jie Luo, Jie Luo, Jie Luo, Shaotang Ye, Shaotang Ye, Shaotang Ye, Jiajun Ou, Jiajun Ou, Jiajun Ou, Xiangbin Wang, Xiangbin Wang, Xiangbin Wang, Haibin Xu, Haibin Xu, Haibin Xu, Ji Huang, Ji Huang, Ji Huang, Liyan Wu, Liyan Wu, Liyan Wu, Xin Zhang, Xin Zhang, Xin Zhang, Peixin Wu, Peixin Wu, Peixin Wu, Shoujun Li, Shoujun Li, Shoujun Li   +36 more
doaj   +1 more source

Nerve growth factor-chondroitin sulfate/hydroxyapatite-coating composite implant induces early osseointegration and nerve regeneration of peri-implant tissues in Beagle dogs

Journal of Orthopaedic Surgery and Research, 2021
Background Osseointegration is the premise of the chewing function of dental implant. Nerve growth factor (NGF), as a neurotrophic factor, can induce bone healing.
Jun Ye, Bo Huang, Ping Gong
doaj   +1 more source

Bisphenol A exposure triggers the malignant transformation of prostatic hyperplasia in beagle dogs via cfa-miR-204/KRAS axis

Ecotoxicology and Environmental Safety, 2022
The prostatic toxicity of bisphenol A (BPA) exposure is mainly associated with hormonal disturbances, thus interfering with multiple signal pathways and increasing the susceptibility to prostatic lesions.
Kaiyue Wang, Dongyan Huang, Ping Zhou, Xin Su, Rongfu Yang, Congcong Shao, Jianhui Wu   +6 more
doaj   +1 more source

Preclinical Drug Pharmacokinetic, Tissue Distribution and Excretion Profiles of the Novel Limonin Derivate HY-071085 as an Anti-Inflammatory and Analgesic Candidate in Rats and Beagle Dogs

Pharmaceuticals, 2022
Limonin is one of the research hotspots in natural drug development. However, its low solubility in water leads to poor oral bioavailability, discouraging the further study of its potential as a candidate compound.
Liping Dong, Wenjuan Liu, Xiaoyuan Zhao, Feng Yu, Yungen Xu, Mengxiang Su   +5 more
doaj   +1 more source