Results 61 to 70 of about 263,543 (279)

Genomic Structural Variations Provide Insights Into Litter Size and Teat Number Traits in Hu Sheep

Animal Research and One Health, EarlyView.
Here, we conducted whole genome sequencing on 300 Hu sheep with an average depth of 16.51X. Two candidate genes associated with litter size and teat number traits were identified, namely MAST2 and AFDN. ABSTRACT Litter size and the teat number are important economic indicators in sheep production.
Xin Xiang, Wei Dai, Jiqiang Liu, Zhengguang Wang   +3 more
wiley   +1 more source

In vitro, in vivo, and in silico approaches for evaluating the preclinical DMPK profiles of ammoxetine, a novel chiral serotonin and norepinephrine reuptake inhibitor

Frontiers in Pharmacology
Background and AimAmmoxetine, a novel chiral serotonin and norepinephrine reuptake inhibitor, holds promise for major depressive disorder treatment. This study aimed to thoroughly investigate its preclinical drug metabolism and pharmacokinetics (DMPK ...
Xiuqing Zhu, Xiuqing Zhu, Yuexin Li, Huan Luo, Yunxia Zhang, Zhenqing Zhang, Jinglai Li   +6 more
doaj   +1 more source

Investigations on Metabolic Changes in Beagle Dogs Fed Probiotic Queso Blanco Cheese and Identification of Candidate Probiotic Fecal Biomarkers Using Metabolomics Approaches

Metabolites, 2020
Intake of probiotic cheese improves the intestinal health of humans and animals. However, metabolic changes in the intestines of dogs in response to the ingestion of probiotic cheese have not been evaluated.
Ye Jin Kim, Ho-Eun Park, Wan-Kyu Lee, Jun-Sang Ham, Sang Un Park, Jae Geun Kim, Kyung-Hoan Im, Jae Kwang Kim   +7 more
doaj   +1 more source

Astragalus polysaccharide (APS) supplement in beagle dogs after castration: Effects on the haematology and serum chemistry profiles, immune response, and oxidative stress status

Veterinary Medicine and Science, 2023
Background Castration is one of the most common surgical procedures performed in dogs. However, based on increasing evidence, male animals experience significant pain after castration. Astragalus polysaccharide (APS), one of the main bioactive components
Jian‐Bo Luo, Lei Zhang, Min Fu, Yang Hong, Xin‐Yin Du, Guo‐Qiang Cheng, Jie‐Ying Xia, Han Dong   +7 more
doaj   +1 more source

A biomechanical optimized Zr58Cu25Al14Nb3 bulk metallic glass dental implant improves peri‐implant stress distribution and bone quality under physiological loading

BMEMat, EarlyView.
This study reports a novel Zr58Cu25Al14Nb3 bulk metallic glass that possesses high mechanical strength and low elastic modulus, which further promotes efficient mechanotransduction and significantly improves peri‐implant bone quality upon cyclic occlusal loading.
Yunshu Wu, Feifei Wang, Yuan He, Yaopeng Zhang, Yuhao Zeng, Fu Zheng, Zhanqi Wei, Sukun Tian, Kinon Chen, Baoan Sun, Yuchun Sun   +10 more
wiley   +1 more source

Periodontal microbiology and microbial etiology of periodontal diseases: Historical concepts and contemporary perspectives

Periodontology 2000, EarlyView., 2023
Abstract This narrative review summarizes the collective knowledge on periodontal microbiology, through a historical timeline that highlights the European contribution in the global field. The etiological concepts on periodontal disease culminate to the ecological plaque hypothesis and its dysbiosis‐centered interpretation.
Georgios N. Belibasakis, Daniel Belstrøm, Sigrun Eick, Ulvi K. Gursoy, Anders Johansson, Eija Könönen   +5 more
wiley   +1 more source

Safety of TCMCB07, a melanocortin‐4 antagonist peptide, in dogs with naturally occurring cachexia

Journal of Veterinary Internal Medicine, 2023
Background The melanocortin 4 antagonist TCMCB07 is safe and effective in reversing cachexia caused by sepsis or cancer in rodents. The safety and pharmacokinetics of TCMCB07 are demonstrated in healthy beagle dogs.
Sandra M. Axiak‐Bechtel, Stacey B. Leach, Jessica R. Newton‐Northup, Rowan J. Milner, Stacey A. Fox‐Alvarez, Lana I. Fagman, Kaylee A. Young, Deborah J. Tate, Zachary M. Wright, John D. Chretin, Justin W. Allen, Sean K. Yoshimoto, Kimberly A. Selting, Brian K. Flesner, Carrie R. White, Tracy Mills, Michael Aherne, Philip J. Bergman, LeAnn Qi, Kenneth A. Gruber, Michael F. Callahan   +20 more
doaj   +1 more source

Experimental periodontitis in the Beagle dog

Journal of Periodontal Research, 1973
The purpose of the present investigation was to study the sequential stages in the development of a periodontal lesion starting from a healthy periodontium. Twenty inbred Beagle dogs 10 months of age and weighing 10–12 kilos were used. The animals were equally divided into one experimental and one control group.
S E, Hamp, J, Lindhe, H, Löe
openaire   +4 more sources

Long‐term outcomes of microsurgical interdental papilla reconstruction: 13‐year and 18‐year case follow‐ups

Clinical Advances in Periodontics, EarlyView.
Abstract Background Loss of the interdental papilla compromises esthetics, speech, and hygiene, significantly affecting quality of life and psychological well‐being. Reconstruction has long been considered unpredictable, particularly in Cairo RT3 cases with advanced interproximal bone loss.
Katsuhiko Akiyama
wiley   +1 more source

Europe's contribution to the evaluation of the use of systemic antimicrobials in the treatment of periodontitis

Periodontology 2000, EarlyView., 2023
Abstract This narrative review celebrates Europe's contribution to the current knowledge on systemically administered antimicrobials in periodontal treatment. Periodontitis is the most frequent chronic noncommunicable human disease. It is caused by dysbiotic bacterial biofilms and is commonly treated with subgingival instrumentation.
David Herrera, Arie Jan van Winkelhoff, Paula Matesanz, Katalina Lauwens, Wim Teughels   +4 more
wiley   +1 more source