Results 51 to 60 of about 6,823,654 (239)

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

RoboFinch: A versatile audio‐visual synchronised robotic bird model for laboratory and field research on songbirds

Methods in Ecology and Evolution, 2023
Singing in birds is accompanied by beak, head and throat movements. The role of these visual cues has long been hypothesised to be an important facilitator in vocal communication, including social interactions and song acquisition, but has seen little ...
Ralph Simon, Judith Varkevisser, Ezequiel Mendoza, Klaus Hochradel, Rogier Elsinga, Peter G. Wiersma, Esmee Middelburg, Eva Zoeter, Constance Scharff, Katharina Riebel, Wouter Halfwerk   +10 more
doaj   +1 more source

“Cave-in” decompression under unilateral biportal endoscopy in a patient with upper thoracic ossification of posterior longitudinal ligament: Case report

Frontiers in Surgery, 2023
BackgroundThoracic ossification of the posterior longitudinal ligament (TOPLL) requires surgery for spinal cord decompression. Traditional open surgery is extremely invasive and has various complications.
Xiaowei Jing, Zhiyuan Gong, Xiaowen Qiu, Zhuolin Zhong, ZiChuan Ping, Qingfeng Hu   +5 more
doaj   +1 more source

Detailed monitoring of a small but recovering population reveals sublethal effects of disease and unexpected interactions with supplemental feeding [PDF]

, 2015
Infectious diseases are widely recognized to have substantial impact on wildlife populations. These impacts are sometimes exacerbated in small endangered populations, and therefore, the success of conservation reintroductions to aid the recovery of such ...
Richards, Heather, Tollington, S, Groombridge, JJ, Smith, Donal, Jones, Carl G., Smith, D, Greenwood, A, Tollington, Simon, Chowrimootoo, Aurélie, Hoeck, P, Groombridge, Jim J., Tatayah, V, Greenwood, Andrew, Richards, H, Jones, CG, Hoeck, Paquita, Tatayah, Vikash, Chowrimootoo, A   +17 more
core   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Production Indicators and Levels of Corticosterone in Pullets Treated with Beak-Trimming Protocols

Brazilian Journal of Poultry Science
The aim of this study was to compare the effects of beak trimming by hot blade or infrared radiation on production indicators and plasma levels of corticosterone in pullets.
JA Vieira Filho, EA Garcia, E Oba, TA Santos, AB Molino, AP Silva, K Pelícia, ICLA Paz   +7 more
doaj   +1 more source

Hallermann–Streiff syndrome: Case report with abnormal pulp calcifications

Frontiers in Dental Medicine, 2022
Hallermann–Streiff syndrome (HSS) is a disorder of rare occurrence affecting the craniofacial complex, with approximately 200 cases reported in the literature. Nonetheless, its distinctive facial features render it highly recognizable.
Nour Ammar, Magda M. El-Tekeya
doaj   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Surgical Fixation of Calcaneal Beak Fractures—Biomechanical Analysis of Different Osteosynthesis Techniques

Frontiers in Bioengineering and Biotechnology, 2022
The calcaneal beak fracture is a rare avulsion fracture of the tuber calcanei characterized by a solid bony fragment at the Achilles tendon insertion. Treatment usually requires osteosynthesis.
Martin C. Jordan, Lukas Hufnagel, Miriam McDonogh, Mila M. Paul, Jonas Schmalzl, Eva Kupczyk, Hendrik Jansen, Philipp Heilig, Rainer H. Meffert, Stefanie Hoelscher-Doht   +9 more
doaj   +1 more source