Results 121 to 130 of about 573,045 (266)
Canned goods at the Newark Big Bear location
, 1940 Canned goods at the Newark, Ohio Big Bear location. This store opened on July 1, 1940 and was remodeled in September of 1962. Big Bear is responsible for many innovations in the supermarket business.
Big Bear
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RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Stacked cans display at Big Bear grocery store
, 1934 In 1934, an innovation in food retailing was introduced to Columbus when Wayne E. Brown opened the first self-service supermarket in central Ohio. Brown leased a 70,000 square foot building on Lane Avenue.
Big Bear
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Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach +23 more
wiley +1 more source
Color photograph of the Big Bear 1958 nerve center
, 1953 Color photo from Big Bear Stores annual report in 1958, showing the memory drum used in connection with the RAMAC computer. The description reads, "At left is the fabuous memory drum used in con-nection with the RAMAC equipment on which is recorded the ...
Big Bear
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Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito +8 more
wiley +1 more source
Photograph of cattle at Big Bear Farms
, 1962 Black and white photograph of cattle and Big Bear stores President, Wayne E. Brown, at Big Bear Farms in Powell, Ohio. Big Bear Farms provided a good portion of the meats offered by the self service Big Bear chain stores. The farm was located near Powell,
Big Bear
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, 1996 56 p. Prepared from Alexander Grosart's The Complete Works in Prose and Verse of Edmund Spenser [1882] by R.S. Bear at the University of Oregon. The text is in the public domain.
Spenser, Edmund, 1552?-1599 +1 more
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White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian +8 more
wiley +1 more source
Canned goods at the North High street Big Bear location
, 1948 Canned goods at 1101 North High Street Big Bear location, in October of 1948. Big Bear is responsible for many innovations in the supermarket business. They were the first to introduce motorized counters that were controlled by the cashier.
Big Bear
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